:root {
  --blue: #164689;
  --navy: #143352;
  --aqua: #6ac7ce;
  --ice: #c1e2ea;
  --sky: #6bc2f1;
  --mid: #5993d6;
  --ink: #42586d;
  --line: #dce7ee;
  --light: #f3f8fb;
  --font: Inter, Arial, sans-serif
}

* {
  box-sizing: border-box
}

html {
  scroll-behavior: smooth;
  scroll-padding-top: 30px
}

body {
  margin: 0;
  font-family: var(--font);
  font-size: 16px;
  line-height: 1.8;
  color: var(--ink);
  background: #fff;
  -webkit-font-smoothing: antialiased
}

button,
a {
  -webkit-tap-highlight-color: transparent
}

button {
  font: inherit
}

a {
  color: var(--blue);
  text-underline-offset: 4px
}

button,
a {
  touch-action: manipulation
}

img {
  display: block;
  max-width: 100%;
  height: auto
}

button {
  cursor: pointer
}

h1,
h2,
h3,
p,
figure,
blockquote {
  margin: 0
}

h1,
h2,
h3 {
  color: var(--navy);
  line-height: 1.15;
  letter-spacing: -.045em
}

h2 {
  font-size: clamp(32px, 3.35vw, 48px);
  font-weight: 650
}

h3 {
  font-size: 23px;
  font-weight: 650;
  letter-spacing: -.025em;
  line-height: 1.35
}

p+p {
  margin-top: 20px
}

p {
  overflow-wrap: break-word
}

sup {
  font-size: .7em;
  line-height: 0;
  white-space: nowrap
}

sup a {
  padding: 0 2px
}

svg {
  display: block
}

.container {
  width: min(1240px, calc(100% - 96px));
  margin-inline: auto
}


.section-intro {
  max-width: 900px;
  margin-bottom: 54px
}

.section-intro h2 {
  max-width: 880px;
  margin-bottom: 25px
}

.section-intro>p {
  max-width: 830px
}

.section-title {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 36px;
  margin-bottom: 45px
}

.section-title.compact h2 {
  font-size: 30px;
  white-space: nowrap
}

.section-rule {
  height: 1px;
  flex: 1;
  background: var(--line)
}

.eyebrow {
  font-size: 11px;
  font-weight: 700;
  letter-spacing: .16em;
  text-transform: uppercase
}

.icon-box {
  width: 52px;
  height: 52px;
  border: 1px solid #b4d8e4;
  border-radius: 14px;
  display: grid;
  place-items: center;
  color: var(--blue);
  background: #f3fafb
}

.icon-box svg {
  width: 31px;
  height: 31px
}

.notice {
  font-size: 12px;
  line-height: 1.8;
  border-top: 1px solid var(--line);
  padding-top: 22px;
  margin-top: 38px;
  color: #617183
}

.skip-link {
  position: fixed;
  left: 20px;
  top: -100px;
  z-index: 20;
  padding: 12px 20px;
  background: #fff;
  border: 2px solid var(--blue)
}

.skip-link:focus {
  top: 15px
}

:focus-visible {
  outline: 3px solid #328eae;
  outline-offset: 5px
}

.site-header {
  height: 95px;
  background: #fff;
  border-bottom: 1px solid #e9f0f4
}

.header-inner {
  display: flex;
  align-items: center;
  justify-content: space-between;
  height: 100%
}

.header-inner>img {
  width: 250px;
  height: auto
}

.ticker {
  background: var(--blue);
  padding: 11px 23px;
  border-radius: 7px;
  color: #fff;
  font-size: 20px;
  letter-spacing: .035em;
  display: flex;
  gap: 12px;
  align-items: center;
  box-shadow: 0 6px 18px #16468913
}

.ticker strong {
  font-size: 24px;
  letter-spacing: .08em
}

.ticker-dot {
  position: relative;
  flex-shrink: 0;
  width: 7px;
  height: 7px;
  background: var(--aqua);
  border-radius: 50%;
  box-shadow: 0 0 0 5px #6ac7ce18
}

.ticker-dot::after {
  content: "";
  position: absolute;
  inset: -3px;
  border: 1px solid var(--aqua);
  border-radius: 50%;
  pointer-events: none;
  animation: ticker-dot-pulse 2s ease-out infinite;
}

@keyframes ticker-dot-pulse {
  0% { transform: scale(.65); opacity: .8; }
  75%, 100% { transform: scale(1.8); opacity: 0; }
}

@media (prefers-reduced-motion: reduce) {
  .ticker-dot::after { display: none; }
}

.hero {
  position: relative;
  overflow: hidden;
  background: radial-gradient(ellipse at 90% 45%, #dbf1f6 0, transparent 54%), linear-gradient(115deg, #fff 25%, #f2f8fc);
  padding: 40px 0 25px
}

.hero-grid {
  display: grid;
  grid-template-columns: 1.12fr 1fr;
  gap: 30px;
  align-items: center;
  /* min-height: 660px */
}

.advertorial {
  display: inline-flex;
  gap: 10px;
  align-items: center;
  color: #526b81;
  margin-bottom: 24px
}

.advertorial:before {
  content: "";
  width: 24px;
  height: 1px;
  background: var(--aqua)
}

.hero h1 {
  font-size: clamp(40px, 4vw, 58px);
  font-weight: 650;
  line-height: 1.08;
  letter-spacing: -.055em
}

.hero h1>span {
  display: block
}

.hero h1 .hero-company {
  font-size: 20px;
  letter-spacing: .01em;
  font-weight: 550;
  margin-bottom: 20px;
  line-height: 1.6
}

.hero .accent-text {
  color: var(--blue)
}

.hero-description {
  font-size: 15px;
  max-width: 570px;
  margin-top: 25px;
  line-height: 1.85
}

.hero-art {
  position: relative;
  width: 100%;
  aspect-ratio: 1;
  isolation: isolate
}

.gene-orb {
  position: absolute;
  inset: 8%;
  border-radius: 50%;
  overflow: hidden;
  background: radial-gradient(circle at 42% 38%, #1a5d85, #0b294d 65%, #112f52);
  box-shadow: inset 0 0 32px #6bc2f149, 0 24px 70px #16468925;
  transform: rotate(-25deg)
}

#gene-canvas {
  width: 100%;
  height: 100%;
  display: block
}

.orbital {
  position: absolute;
  border: 1px solid #5993d650;
  border-radius: 50%;
  inset: 1%;
  transform: rotate(-30deg) scaleY(.73);
  z-index: 2;
  pointer-events: none
}

.orbital-one:after {
  content: "";
  position: absolute;
  top: 18%;
  left: 12%;
  height: 11px;
  width: 11px;
  background: var(--blue);
  border: 3px solid #d9ecf5;
  border-radius: 50%;
  box-shadow: 0 0 0 4px #1646890d
}

.orbital-two {
  inset: -4%;
  transform: rotate(40deg) scaleY(.85);
  border-style: dashed;
  border-color: #5993d638;
  z-index: -1
}

.orbit-label {
  position: absolute;
  background: #ffffffeb;
  backdrop-filter: blur(12px);
  border: 1px solid #fff;
  padding: 10px 18px;
  display: flex;
  align-items: center;
  gap: 12px;
  border-radius: 9px;
  box-shadow: 0 12px 35px #14335212;
  color: var(--navy);
  font-size: 14px;
  font-weight: 600;
  z-index: 3;
  animation: float 7s ease-in-out infinite
}

.orbit-label svg {
  width: 18px;
  height: 18px;
  stroke: var(--blue);
  stroke-width: 1.3;
  fill: none;
  margin-left: 10px
}

.mini-dot {
  width: 7px;
  height: 7px;
  background: var(--aqua);
  border-radius: 50%
}

.label-one {
  left: -1%;
  top: 22%
}

.label-two {
  right: -1%;
  bottom: 22%;
  animation-delay: -3s
}

.label-two .mini-dot {
  background: var(--mid)
}

.orbit-cross {
  position: absolute;
  color: #5993d6;
  font-size: 22px;
  font-weight: 400
}

.cross-one {
  right: 7%;
  top: 4%
}

.cross-two {
  left: 8%;
  bottom: 7%
}

.motion-toggle {
  position: absolute;
  right: 5%;
  bottom: 3%;
  width: 36px;
  height: 36px;
  border: 1px solid #aacbdc;
  border-radius: 50%;
  background: transparent;
  color: var(--navy);
  display: grid;
  place-items: center;
  font-size: 14px
}

.motion-toggle:hover {
  background: #fff
}

.hero-baseline {
  display: flex;
  align-items: center;
  gap: 23px;
  margin-top: 45px;
  font-size: 9px;
  letter-spacing: .16em;
  color: #617b92;
  font-weight: 600
}

.baseline-line {
  height: 1px;
  background: #cfdee8;
  flex: 1
}

.highlights {
  padding: 64px 0 80px
}

.highlights-grid {
  display: grid;
  grid-template-columns: repeat(4, 1fr);
  border: 1px solid var(--line);
  border-radius: 14px;
  overflow: hidden
}

.highlight {
  padding: 30px 25px;
  background: #fff;
  transition: background .25s
}

.highlight+.highlight {
  border-left: 1px solid var(--line)
}

.highlight:hover {
  background: #f3f9fb
}

.highlight .icon-box {
  margin-bottom: 30px
}

.highlight h3 {
  font-size: 18px;
  line-height: 1.45;
  margin-bottom: 16px;
  letter-spacing: -.025em
}

.highlight p {
  font-size: 14px;
  line-height: 1.85
}

.overview {
  background: var(--light)
}

.overview-grid {
  display: grid;
  grid-template-columns: .95fr 1.05fr;
  gap: 76px;
  align-items: center
}

.overview-visual {
  position: relative;
  align-self: stretch;
  min-height: 540px
}

.overview-visual>img {
  width: 100%;
  height: 100%;
  object-fit: cover;
  object-position: 41%;
  border-radius: 16px 80px 16px 16px
}

.visual-corner {
  position: absolute;
  bottom: 25px;
  left: 25px;
  width: 80px;
  height: 80px;
  background: #ffffffd9;
  border-radius: 20px;
  display: grid;
  place-items: center;
  backdrop-filter: blur(12px)
}

.visual-corner svg {
  width: 45px;
  color: var(--blue)
}

.overview-copy h2 {
  margin-bottom: 26px
}

.overview-copy p {
  font-size: 15px;
  line-height: 1.85
}

.dark {
  color: #d4e3ef;
  background: #103859
}

.dark h2,
.dark h3 {
  color: #fff
}

.dark sup a {
  color: #b7e8f0
}

.dark .notice {
  color: #c0d2e0;
  border-color: #ffffff24
}

.reasons {
  position: relative;
  overflow: hidden;
  background: radial-gradient(ellipse at 100% 0, #1c5680, transparent 55%), #103859
}

.reasons .section-title {
  position: relative;
  min-height: 120px
}
.top-reason-head span{color: var(--aqua);}

.reasons .section-title h2 {
  max-width: 660px;
  font-size: clamp(36px, 4vw, 56px);
  position: relative;
  z-index: 1
}

.reason-orbits {
  position: absolute;
  width: 210px;
  height: 210px;
  right: 40px;
  top: -30px
}

.reason-orbits i {
  position: absolute;
  inset: 0;
  border: 1px solid #6ac7ce40;
  border-radius: 50%;
  transform: rotate(-35deg) scaleX(.5)
}

.reason-orbits i:nth-child(2) {
  transform: rotate(25deg) scaleX(.5)
}

.reason-orbits i:nth-child(3) {
  transform: rotate(85deg) scaleX(.5)
}

.reasons-grid {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 18px
}

.reason {
  padding: 34px;
  border: 1px solid #8bbdd82e;
  background: #ffffff05;
  border-radius: 13px;
  display: flex;
  align-items: flex-start;
  gap: 22px;
  transition: background .3s, border-color .3s
}

.reason:hover {
  background: #ffffff0c;
  border-color: #6ac7ce70
}

.reason-index {
  flex-shrink: 0;
  width: 43px;
  height: 43px;
  border: 1px solid #70bddb4d;
  color: #8fdae2;
  border-radius: 50%;
  display: grid;
  place-items: center;
}

.reason h3 {
  font-size: 21px;
  margin-bottom: 15px
}

.reason p {
  font-size: 14px;
  line-height: 1.85;
  color: #cfdeea
}

.reason-1 {
  grid-column: 1/-1;
  background: linear-gradient(110deg, #1e5e7e, #174368);
  padding: 40px
}

.reason-1>div {
  max-width: 900px
}

.reason-1 h3 {
  font-size: 26px
}

.reason-1 .reason-index {
  background: #6ac7ce;
  color: #143352;
  border: 0
}

.challenges {
  background: #fff
}

.challenge-grid {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 28px
}

.challenge {
  border: 1px solid var(--line);
  border-radius: 16px;
  overflow: hidden;
  background: #fff
}

.challenge-image {
  height: 210px;
  background-size: cover;
  background-position: center
}

.challenge-image.lung {
  background-image: linear-gradient(0deg, #16468924, #16468924), url('../images/shutterstock_1187881555.jpg')
}

.challenge-image.diabetes {
  background-image: url('../images/shutterstock_2464647841.jpg')
}

.challenge-body {
  padding: 32px
}

.challenge h3 {
  font-size: 25px;
  margin-bottom: 20px
}

.challenge p {
  font-size: 15px
}

.challenge .document-figure {
  margin-top: 28px
}

.document-figure {
  min-width: 0;
  margin: 0
}

.image-zoom {
  display: block;
  position: relative;
  width: 100%;
  background: #fff;
  border: 0;
  padding: 0;
  text-align: left;
  border-radius: 8px;
  overflow: hidden;
  cursor: zoom-in
}

.image-zoom img {
  width: 100%;
  height: auto
}

.zoom-symbol {
  position: absolute;
  right: 9px;
  bottom: 9px;
  border: 1px solid #cddfe9;
  width: 31px;
  height: 31px;
  border-radius: 50%;
  display: grid;
  place-items: center;
  background: #fffffff0;
  color: var(--blue);
  font-size: 18px;
  transition: transform .2s
}

.image-zoom:hover .zoom-symbol {
  transform: scale(1.1)
}

.science {
  background: var(--light)
}

.science-row {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 70px;
  align-items: center;
  margin-top: 66px
}

.science-copy .icon-box {
  margin-bottom: 24px
}

.science-copy h3 {
  font-size: 29px;
  margin-bottom: 23px
}

.science-copy p {
  font-size: 15px
}

.science-row .document-figure {
  background: #fff;
  border: 1px solid var(--line);
  padding: 22px;
  border-radius: 18px;
  box-shadow: 0 18px 40px #14335205
}

.science-row.reverse .science-copy {
  order: 2
}

.quote-panel {
  margin-top: 76px;
  background: #e3f0f4;
  border-radius: 16px;
  padding: 42px;
  display: flex;
  gap: 35px
}

.quote-person {
  width: 95px;
  flex-shrink: 0;
  position: relative;
  align-self: flex-start
}

.quote-person img {
  border-radius: 50%;
  width: 88px;
  height: 88px;
  object-fit: cover;
  object-position: top
}

.quote-person>span {
  font-family: Georgia, serif;
  font-size: 95px;
  color: #448caa;
  line-height: 1px;
  display: block;
  text-align: center;
  margin-top:50px
}

.quote-panel blockquote p {
  font-size: 16px;
  line-height: 1.9;
  color: var(--navy)
}

.quote-panel cite {
  display: block;
  font-size: 12px;
  font-style: normal;
  font-weight: 600;
  margin-top: 22px;
  color: var(--blue)
}

.clinical-grid {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 28px
}

.trial-card {
  background: var(--light);
  border: 1px solid var(--line);
  border-radius: 16px;
  padding: 35px;
  overflow: hidden
}

.trial-top {
  display: flex;
  justify-content: space-between;
  align-items: center;
  border-bottom: 1px solid var(--line);
  padding-bottom: 20px;
  margin-bottom: 25px;
  color: var(--blue);
  font-weight: 600;
  letter-spacing: .13em;
  font-size: 12px
}

.trial-top svg {
  width: 30px
}

.trial-card h3 {
  font-size: 27px;
  margin-bottom: 22px
}

.trial-card p {
  font-size: 15px
}

.trial-card .document-figure {
  margin-top: 25px
}

.trial-card:nth-child(2) {
  background: #edf7f7
}

.trial-decoration {
  height: 180px;
  margin-top: 30px;
  display: flex;
  justify-content: center;
  align-items: center;
  gap: 16px;
  transform: rotate(-15deg)
}

.trial-decoration i {
  height: 60px;
  width: 23px;
  border-radius: 20px;
  background: linear-gradient(#6ac7ce, #164689)
}

.trial-decoration i:nth-child(2),
.trial-decoration i:nth-child(5) {
  height: 110px;
  opacity: .7
}

.trial-decoration i:nth-child(3),
.trial-decoration i:nth-child(4) {
  height: 150px;
  opacity: .5
}

.clinical-conclusion {
  margin-top: 36px;
  display: grid;
  grid-template-columns: 1fr 2fr;
  gap: 40px;
  border-left: 3px solid var(--aqua);
  padding: 25px 30px
}

.clinical-conclusion h3 {
  font-size: 23px
}

.clinical-conclusion p {
  font-size: 15px
}

.pipeline {
  background: #f4f8fb;
  border-top: 1px solid #e9f0f4
}

.pipeline-frame {
  background: #fff;
  padding: 24px;
  border: 1px solid var(--line);
  border-radius: 18px
}

.pipeline-frame .document-figure {
  max-width: 1120px;
  margin: auto
}

.market {
  background: radial-gradient(ellipse at 80% 0, #225d83, transparent 65%), #103859
}


.market-grid {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 60px
}

.market-card {
  border-top: 1px solid #b5d5e447;
  padding-top: 26px
}

.market-number {
  font-size: clamp(70px, 7.3vw, 106px);
  font-weight: 500;
  letter-spacing: -.07em;
  line-height: 1.4;
  color: #bce9ed;
  display: flex;
  align-items: baseline
}

.market-number span {
  font-size: .6em;
  color: #6ac7ce;
  margin-left: 6px
}

.market-number svg {
  width: 50px;
  height: 50px;
  stroke: #6ac7ce;
  stroke-width: 1.5;
  fill: none;
  margin-left: auto;
  align-self: center
}

.market-card h3 {
  font-size: 26px;
  margin: 18px 0
}

.market-card p {
  font-size: 15px
}

.development-layout {
  display: grid;
  grid-template-columns: .8fr 1.2fr;
  gap: 65px
}

.development-photo {
  position: relative;
  min-height: 600px;
  border-radius: 18px;
  overflow: hidden
}

.development-photo>img {
  height: 100%;
  width: 100%;
  object-fit: cover;
  object-position: 35%
}

.photo-grid {
  position: absolute;
  inset: 0;
  background: linear-gradient(0deg, #164689bb, transparent 60%)
}

.photo-grid:after {
  content: "";
  position: absolute;
  width: 170px;
  height: 170px;
  left: 35px;
  bottom: 35px;
  border: 1px solid #ffffff70;
  border-radius: 50%;
  box-shadow: 0 0 0 25px #ffffff15, 0 0 0 50px #ffffff10
}

.timeline {
  position: relative
}

.timeline:before {
  content: "";
  position: absolute;
  left: 20px;
  top: 20px;
  bottom: 30px;
  background: var(--line);
  width: 1px
}

.development {
  display: flex;
  gap: 25px;
  position: relative;
  padding-bottom: 36px
}

.development:last-child {
  padding-bottom: 0
}

.timeline-node {
  width: 41px;
  height: 41px;
  border: 1px solid #c4dde6;
  border-radius: 50%;
  background: #f0f7fa;
  color: var(--blue);
  display: grid;
  place-items: center;
  flex-shrink: 0;
  font-size: 12px;
  font-weight: 600
}

.development h3 {
  font-size: 21px;
  margin-bottom: 14px
}

.development p {
  font-size: 14px
}

.development p+p {
  margin-top: 12px
}

.compact-quote {
  margin-top: 50px
}

.compact-quote .quote-person>span {
  display: none
}

.milestones {
  background: #f2f7fa
}

.milestone-list {
  border-top: 1px solid #c8dce6
}

.milestone {
  display: flex;
  gap: 32px;
  padding: 31px 0;
  border-bottom: 1px solid #c8dce6;
  align-items: flex-start
}

.milestone-number {
  font-size: 30px;
  color: #73a4be;
  letter-spacing: -.06em;
  min-width: 55px;
  line-height: 1.4
}

.milestone h3 {
  font-size: 22px;
  margin-bottom: 13px
}

.milestone p {
  font-size: 14px;
  max-width: 1000px
}

.milestone-plus {
  color: #6697b2;
  font-size: 28px;
  margin-left: auto;
  line-height: 1.4
}

.company-grid {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 76px
}

.company-heading .eyebrow {
  margin-bottom: 20px;
  color: var(--blue)
}

.company-heading h2 {
  font-size: 44px
}

.company-heading>img {
  margin-top: 35px;
  height: 240px;
  width: 100%;
  object-fit: cover;
  border-radius: 12px
}

.company-copy {
  padding-top: 33px
}

.company-copy p {
  font-size: 15px
}

.team-heading {
  display: flex;
  align-items: center;
  gap: 35px;
  margin: 70px 0 30px
}

.team-heading h2 {
  font-size: 30px
}

.team-panels {
  display: grid;
  grid-template-columns: 1.4fr 1fr;
  gap: 28px;
  align-items: start
}

.team-panels .document-figure {
  padding: 10px;
  border: 1px solid var(--line);
  border-radius: 12px
}

.news {
  background: #f4f8fb;
  padding-top: 75px;
  padding-bottom: 75px
}

.news-link {
  display: grid;
  grid-template-columns: 50px 1fr 40px;
  gap: 20px;
  align-items: center;
  padding: 24px 4px;
  border-bottom: 1px solid var(--line);
  text-decoration: none;
  transition: color .2s, background .2s
}

.news-link:hover {
  background: #e8f2f8;
  color: #0a5277
}

.news-link>span[data-source-p] {
  font-size: 14px;
  overflow-wrap: anywhere;
  line-height: 1.7
}

.news-number {
  font-size: 12px;
  color: #6a8fa5
}

.news-arrow {
  font-size: 25px;
  text-align: right
}

.summary {
  padding-bottom: 70px
}

.summary-layout {
  display: grid;
  grid-template-columns: 1fr 2fr;
  gap: 70px
}

.summary-symbol {
  margin-top: 35px;
  width: 130px;
  height: 130px;
  border: 1px solid #cee4ed;
  border-radius: 50%;
  display: grid;
  place-items: center;
  background: #f2f8fb
}

.summary-symbol svg {
  width: 68px;
  color: var(--blue)
}

.summary-layout p {
  font-size: 15px
}

.closing {
  overflow: hidden;
  position: relative;
  text-align: center;
  background: radial-gradient(ellipse at 50% 120%, #267d98, transparent 70%), #113c64
}

.closing>.container {
  position: relative
}

.closing h2 {
  max-width: 1000px;
  margin: 0 auto;
  font-size: clamp(27px, 3vw, 38px);
  line-height: 1.4;
  letter-spacing: -.035em
}

.closing-orbits {
  position: absolute;
  inset: -70px 30%;
  border: 1px solid #81c4d21c;
  border-radius: 50%;
  transform: rotate(40deg);
  pointer-events: none;
  box-shadow: 0 0 0 60px #81c4d209, 0 0 0 120px #81c4d207
}

.closing-actions {
  position: relative;
  display: flex;
  flex-direction: column;
  align-items: center;
  margin-top: 35px;
  gap: 18px
}

.button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 35px;
  text-decoration: none;
  padding: 16px 25px;
  font-size: 14px;
  font-weight: 600;
  border-radius: 6px;
  transition: transform .2s, background .2s
}

.primary-button {
  background: var(--ice);
  color: var(--navy)
}

.primary-button:hover {
  background: #fff;
  transform: translateY(-3px)
}

.primary-button>span:last-child {
  font-size: 21px
}

.presentation-url {
  color: #c9e3ef;
  font-size: 11px;
  overflow-wrap: anywhere;
  max-width: 100%
}

.resource-links {
  position: relative;
  display: flex;
  justify-content: center;
  gap: 30px;
  flex-wrap: wrap;
  margin-top: 28px
}

.resource-links a {
  color: #d6e9f2;
  font-size: 14px;
  overflow-wrap: anywhere
}

.sources {
  padding: 50px 0
}

.sources h2 {
  font-size: 19px;
  margin-bottom: 22px
}

.sources ol {
  list-style: none;
  padding: 0;
  margin: 0;
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 12px 40px
}

.sources li {
  font-size: 11px;
  display: flex;
  gap: 14px;
  scroll-margin-top: 30px
}

.sources li:target {
  background: #e3f4f8;
  outline: 5px solid #e3f4f8
}

.source-number {
  min-width: 18px;
  color: #7792a6
}

.sources a {
  overflow-wrap: anywhere;
  color: #577287
}

.site-footer {
  border-top: 1px solid var(--line);
  padding: 24px 0;
  text-align: center;
  font-size: 11px;
  color: #72889b
}

.image-dialog {
  border: 0;
  padding: 55px 20px 20px;
  border-radius: 12px;
  background: #fff;
  max-width: 95vw;
  max-height: 93vh;
  width: max-content;
  overflow: auto;
  box-shadow: 0 25px 100px #0005
}

.image-dialog::backdrop {
  background: #102e4be6;
  backdrop-filter: blur(6px)
}

.image-dialog>img {
  max-width: 100%;
  width: auto;
  max-height: 76vh;
  object-fit: contain
}

.dialog-close {
  position: absolute;
  right: 13px;
  top: 7px;
  width: 40px;
  height: 40px;
  border: 0;
  background: #edf5f8;
  color: var(--navy);
  font-size: 27px;
  border-radius: 50%;
  line-height: normal;
}

body.dialog-open {
  overflow: hidden
}

.reveal {
  transition: opacity .7s ease, transform .7s ease
}

.reveal-pending {
  opacity: 0;
  transform: translateY(22px)
}

@keyframes float {

  0%,
  100% {
    transform: translateY(0)
  }

  50% {
    transform: translateY(-12px)
  }
}

.motion-paused * {
  animation-play-state: paused !important
}

.motion-paused .reveal {
  transition: none
}

@media(min-width:1600px) {
  .hero-grid {
    min-height: 700px
  }

  .hero-art {
    width: 105%
  }
}

@media(max-width:1100px) {
  .container {
    width: calc(100% - 64px)
  }

  .hero-grid {
    gap: 10px;
    min-height: 640px;
    grid-template-columns: 1.1fr 1fr
  }

  .hero h1 {
    font-size: 49px
  }

  .hero-art {
    margin-left: 10px
  }

  .hero-description {
    font-size: 14px
  }

  .highlight {
    padding: 25px 19px
  }

  .highlight h3 {
    font-size: 16px
  }

  .overview-grid {
    gap: 40px
  }

  .reason {
    padding: 25px;
    gap: 17px
  }

  .reason h3 {
    font-size: 20px
  }

  .science-row {
    gap: 40px
  }

  .development-layout {
    gap: 35px
  }

  .company-grid {
    gap: 40px
  }

  .team-panels {
    grid-template-columns: 1fr
  }

  .team-panels .document-figure:last-child {
    max-width: 70%;
    justify-self: center
  }
}

@media(max-width:800px) {
  .container {
    width: calc(100% - 48px)
  }

  .section {
    padding: 72px 0
  }

  .site-header {
    height: 88px
  }

  .header-inner>img {
    width: 170px
  }

  .ticker {
    padding: 9px 15px;
    font-size: 14px
  }

  .ticker strong {
    font-size: 18px
  }

  .hero {
    padding-top: 40px
  }

  .hero-grid {
    grid-template-columns: 1fr;
    gap: 8px
  }

  .hero-copy {
    max-width: 620px
  }

  .hero h1 {
    font-size: 58px
  }

  .hero-description {
    max-width: 600px;
    font-size: 15px
  }

  .hero-art {
    width: min(490px, 90%);
    margin: 10px auto 0
  }

  .hero-baseline {
    margin-top: 20px
  }

  .highlights-grid {
    grid-template-columns: 1fr 1fr
  }

  .highlight {
    padding: 27px
  }

  .highlight:nth-child(3) {
    border-left: 0
  }

  .highlight:nth-child(n+3) {
    border-top: 1px solid var(--line)
  }

  .highlight h3 {
    font-size: 18px
  }

  .highlight p {
    font-size: 14px
  }

  .highlight .icon-box {
    margin-bottom: 22px
  }

  .overview-grid {
    grid-template-columns: 1fr;
    gap: 35px
  }

  .overview-visual {
    min-height: 0;
    height: 360px
  }

  .overview-visual>img {
    object-position: center 40%
  }

  .overview-copy p {
    font-size: 15px
  }

  .reasons-grid {
    grid-template-columns: 1fr
  }

  .reason-1 {
    grid-column: auto
  }

  .reason {
    padding: 30px
  }

  .reason-1 h3 {
    font-size: 22px
  }

  .reason-orbits {
    right: -60px;
    opacity: .5
  }

  .reasons .section-title h2 {
    max-width: 570px
  }

  .challenge-grid,
  .clinical-grid {
    grid-template-columns: 1fr
  }

  .challenge-image {
    height: 240px
  }

  .challenge-body {
    padding: 30px
  }

  .challenge .document-figure {
    max-width: 540px;
    margin-inline: auto
  }

  .science-row {
    grid-template-columns: 1fr;
    gap: 30px;
    margin-top: 48px
  }

  .science-row.reverse .science-copy {
    order: 0
  }

  .science-row .document-figure {
    max-width: 570px;
    width: 100%;
    margin: auto
  }

  .quote-panel {
    padding: 28px;
    gap: 23px
  }

  .quote-person {
    width: 65px
  }

  .quote-person img {
    width: 65px;
    height: 65px
  }

  .quote-panel blockquote p {
    font-size: 15px
  }

  .trial-decoration {
    height: 130px
  }

  .clinical-conclusion {
    grid-template-columns: 1fr;
    gap: 15px
  }

  .market-grid {
    gap: 32px
  }

  .market-number {
    font-size: 73px
  }

  .market-card h3 {
    font-size: 23px
  }

  .development-layout {
    grid-template-columns: 1fr
  }

  .development-photo {
    min-height: 0;
    height: 280px
  }

  .development-photo>img {
    object-position: center 40%
  }

  .development-photo .photo-grid {
    display: none
  }

  .company-grid {
    grid-template-columns: 1fr;
    gap: 10px
  }

  .company-heading h2 {
    font-size: 39px;
    max-width: 530px
  }

  .company-heading>img {
    height: 280px
  }

  .company-copy {
    padding-top: 20px
  }

  .summary-layout {
    grid-template-columns: 1fr;
    gap: 30px
  }

  .summary-symbol {
    display: none
  }

  .sources ol {
    grid-template-columns: 1fr
  }

  .section-intro {
    margin-bottom: 37px
  }

  .section-intro h2 {
    margin-bottom: 22px
  }
}

@media(max-width:480px) {
  body {
    font-size: 15px
  }

  .container {
    width: calc(100% - 36px)
  }

  .section {
    padding: 57px 0
  }

  .site-header {
    height: 80px
  }

  .header-inner>img {
    width: 160px
  }

  .ticker {
    gap: 9px;
    padding: 8px 11px;
    border-radius: 5px;
    font-size: 13px
  }

  .ticker strong {
    font-size: 16px
  }

  .ticker-dot {
    width: 5px;
    height: 5px;
    box-shadow: 0 0 0 3px #6ac7ce18
  }

  .hero {
    padding-top: 30px
  }

  .advertorial {
    font-size: 9px;
    margin-bottom: 19px
  }

  .hero h1 {
    font-size: clamp(34px, 9.4vw, 45px);
    line-height: 1.12;
    letter-spacing: -.052em
  }

  .hero h1 .hero-company {
    font-size: 12px;
    margin-bottom: 17px
  }

  .hero-description {
    font-size: 13px;
    line-height: 1.85;
    margin-top: 22px
  }

  .hero-art {
    width: 96%;
    margin-top: 20px
  }

  .orbit-label {
    font-size: 11px;
    padding: 10px 12px;
    gap: 8px
  }

  .orbit-label svg {
    width: 15px;
    margin-left: 0
  }

  .label-one {
    left: 0
  }

  .label-two {
    right: 0
  }

  .motion-toggle {
    width: 32px;
    height: 32px
  }

  .hero-baseline {
    font-size: 7px;
    gap: 12px
  }

  .hero-baseline>span:last-child {
    max-width: 130px;
    text-align: right;
    line-height: 1.6
  }

  .highlights {
    padding: 42px 0 55px
  }

  .section-title.compact h2 {
    font-size: 25px;
    white-space: normal
  }

  .section-title {
    gap: 22px;
    margin-bottom: 28px
  }

  .highlights-grid {
    grid-template-columns: 1fr
  }

  .highlight {
    padding: 25px
  }

  .highlight+.highlight {
    border-left: 0;
    border-top: 1px solid var(--line)
  }

  .highlight .icon-box {
    float: left;
    margin: 0 18px 12px 0;
    width: 44px;
    height: 44px;
    border-radius: 12px
  }

  .highlight .icon-box svg {
    width: 26px
  }

  .highlight h3 {
    min-height: 51px;
    font-size: 17px;
    margin-bottom: 14px
  }

  .highlight p {
    clear: both;
    font-size: 13px
  }

  .overview-visual {
    height: 290px
  }

  .overview-visual>img {
    border-top-right-radius: 55px
  }

  .overview-copy p {
    font-size: 14px
  }

  h2 {
    font-size: 32px
  }

  .notice {
    font-size: 11px;
    margin-top: 28px;
    padding-top: 20px
  }

  .reasons .section-title {
    min-height: 0;
    margin-bottom: 32px
  }

  .reasons .section-title h2 {
    font-size: 36px
  }

  .reason-orbits {
    display: none
  }

  .reason {
    padding: 24px 21px;
    display: block
  }

  .reason-index {
    width: 35px;
    height: 35px;
    margin-bottom: 19px;
    font-size: 10px
  }

  .reason h3,
  .reason-1 h3 {
    font-size: 21px
  }

  .reason p {
    font-size: 13px
  }

  .challenge-body {
    padding: 24px
  }

  .challenge-image {
    height: 190px
  }

  .challenge h3 {
    font-size: 23px
  }

  .challenge p {
    font-size: 13px
  }

  .science-copy h3 {
    font-size: 25px
  }

  .science-copy p {
    font-size: 14px
  }

  .science-row .document-figure {
    padding: 10px
  }

  .quote-panel {
    margin-top: 42px;
    padding: 24px;
    display: block
  }

  .quote-person {
    width: auto;
    display: flex;
    align-items: center;
    gap: 20px;
    margin-bottom: 20px
  }

  .quote-person>span {
    font-size: 75px;
    height: 55px;
    margin: 0
  }

  .quote-panel blockquote p {
    font-size: 14px
  }

  .quote-panel cite {
    font-size: 11px
  }

  .trial-card {
    padding: 25px
  }

  .trial-card h3 {
    font-size: 24px
  }

  .trial-card p {
    font-size: 13px
  }

  .clinical-conclusion {
    padding: 15px 20px
  }

  .clinical-conclusion p {
    font-size: 13px
  }

  .pipeline-frame {
    padding: 9px
  }

  .market-grid {
    grid-template-columns: 1fr;
    gap: 30px
  }

  .market-number {
    font-size: 88px
  }

  .market-number svg {
    width: 42px
  }

  .market-card h3 {
    font-size: 23px
  }

  .market-card p {
    font-size: 14px
  }

  .development-photo {
    height: 230px
  }

  .development {
    gap: 17px
  }

  .development h3 {
    font-size: 20px
  }

  .development p {
    font-size: 13px
  }

  .timeline-node {
    width: 34px;
    height: 34px;
    font-size: 10px
  }

  .timeline:before {
    left: 17px
  }

  .milestone {
    gap: 15px;
    padding: 25px 0
  }

  .milestone-number {
    font-size: 23px;
    min-width: 28px
  }

  .milestone-plus {
    display: none
  }

  .milestone h3 {
    font-size: 20px
  }

  .milestone p {
    font-size: 13px
  }

  .company-heading h2 {
    font-size: 34px
  }

  .company-copy p {
    font-size: 14px
  }

  .company-heading>img {
    height: 230px
  }

  .team-heading {
    margin-top: 42px
  }

  .team-panels {
    gap: 15px
  }

  .team-panels .document-figure {
    padding: 4px
  }

  .team-panels .document-figure:last-child {
    max-width: 100%;
    width: 100%
  }

  .news-link {
    grid-template-columns: 23px 1fr 20px;
    gap: 10px;
    padding: 19px 0
  }

  .news-link>span[data-source-p] {
    font-size: 12px
  }

  .news-arrow {
    font-size: 20px
  }

  .summary-layout p {
    font-size: 14px
  }

  .closing h2 {
    font-size: 26px
  }

  .resource-links {
    gap: 16px;
    flex-direction: column
  }

  .resource-links a {
    font-size: 12px
  }

  .presentation-url {
    font-size: 10px
  }

  .sources {
    padding: 36px 0
  }

  .sources li {
    font-size: 10px;
    gap: 8px
  }

  .image-dialog {
    padding: 10px 8px 10px;
    width: 96vw;
    max-width: 96vw
  }

  .image-dialog>img {
    max-width: none;
    min-width: 100%;
    max-height: none;
    width: 900px
  }

  .image-dialog {
    overscroll-behavior: contain
  }

  .dialog-close {
    position: sticky;
    left: calc(100% - 45px);
    top: 0;
    display: block;
    margin-top: -43px;
    margin-bottom: 7px;
    line-height: normal;
  }
}

@media(prefers-reduced-motion:reduce) {
  html {
    scroll-behavior: auto
  }

  *,
  *:before,
  *:after {
    animation: none !important;
    transition: none !important
  }

  .reveal-pending {
    opacity: 1;
    transform: none
  }
}

/* Full-width dark hero adapted from the supplied animated DNA design. */
.hero--dark {
  isolation: isolate;
  background: radial-gradient(ellipse at 79% 38%, #16468988, transparent 58%), radial-gradient(ellipse at 8% 100%, #6ac7ce1c, transparent 55%), linear-gradient(145deg, #0a1c30, #143352);
  color: var(--ice);
}

.hero--dark::after {
  content: "";
  position: absolute;
  inset: 0;
  z-index: 1;
  pointer-events: none;
  background: linear-gradient(90deg, #0a1c307a 0%, #0a1c302e 43%, transparent 64%)
}

.hero--dark #gene-canvas {
  position: absolute;
  inset: 0;
  z-index: 0;
  width: 100%;
  height: 100%;
  pointer-events: none
}

.hero-aura {
  position: absolute;
  z-index: 0;
  border-radius: 50%;
  filter: blur(70px);
  pointer-events: none;
  animation: hero-drift 18s ease-in-out infinite alternate
}

.aura-aqua {
  width: 36vw;
  height: 36vw;
  background: var(--aqua);
  left: -8vw;
  bottom: -20vw;
  opacity: .16
}

.aura-blue {
  width: 30vw;
  height: 30vw;
  background: var(--mid);
  right: -6vw;
  top: -13vw;
  opacity: .2;
  animation-delay: -8s
}

.hero--dark .hero-grid {
  position: relative;
  z-index: 2
}

.hero--dark .hero-copy {
  max-width: 650px
}

.hero--dark h1 {
  color: #f2f9fc
}

.hero--dark h1 .hero-company {
  color: var(--ice)
}

.hero--dark .accent-text {
  color: var(--aqua);
  background: linear-gradient(110deg, var(--aqua), var(--sky) 75%, var(--ice));
  background-clip: text;
  -webkit-background-clip: text;
  -webkit-text-fill-color: transparent
}

.hero--dark .advertorial {
  color: #a5c8da
}

.hero--dark .advertorial:before {
  box-shadow: 0 0 14px #6ac7ce70
}

.hero--dark .hero-description {
  color: #e8f7ff
}

.hero--dark sup a {
  color: var(--ice)
}

.hero--dark .hero-art {
  width: 100%;
  height: 590px;
  aspect-ratio: auto;
  margin: 0;
  align-self: center;
  isolation: auto;
  pointer-events: none
}

.hero-legend {
  position: absolute;
  bottom: 0;
  left: 50%;
  transform: translateX(-50%);
  display: flex;
  gap: 25px;
  white-space: nowrap;
  font-size: 12px;
  color: #bed9e7
}

.hero-legend span {
  display: flex;
  gap: 9px;
  align-items: center
}

.hero-legend i {
  width: 7px;
  height: 7px;
  border-radius: 50%;
  background: var(--aqua);
  box-shadow: 0 0 12px #6ac7ce80
}

.hero-legend span:last-child i {
  background: var(--sky);
  box-shadow: 0 0 12px #6bc2f180
}

.hero--dark .motion-toggle {
  pointer-events: auto;
  right: 0;
  bottom: -7px;
  width: 40px;
  height: 40px;
  border-color: #6bc2f14a;
  background: #14335290;
  color: var(--ice);
  backdrop-filter: blur(8px)
}

.hero--dark .motion-toggle:hover {
  background: #164689
}

.hero--dark .hero-baseline {
  position: relative;
  z-index: 2;
  color: #9fc4d8
}

.hero--dark .baseline-line {
  background: #c1e2ea26
}

@keyframes hero-drift {
  to {
    transform: translate(4vw, -3vw) scale(1.15)
  }
}

@media(max-width:1100px) and (min-width:801px) {
  .hero--dark .hero-art {
    height: 570px
  }

  .hero--dark .hero-copy {
    position: relative
  }

  .hero--dark::after {
    background: linear-gradient(90deg, #0a1c30b3, #0a1c3055 52%, transparent 72%)
  }
}

@media(max-width:800px) {
  .hero--dark .hero-grid {
    gap: 8px;
    min-height: 0
  }

  .hero--dark .hero-art {
    height: 400px;
    margin-top: 14px
  }

  .hero--dark::after {
    background: linear-gradient(180deg, #0a1c3055, transparent 65%)
  }

  .hero--dark .hero-legend {
    bottom: 18px
  }

  .hero--dark .motion-toggle {
    bottom: 10px;
    right: 4%
  }

  .hero--dark .hero-baseline {
    margin-top: 22px
  }

  .aura-aqua {
    width: 70vw;
    height: 70vw;
    bottom: -30vw
  }

  .aura-blue {
    width: 60vw;
    height: 60vw;
    top: 35%;
    right: -35vw
  }
}

@media(max-width:480px) {
  .hero--dark .hero-art {
    height: 320px;
    margin-top: 12px
  }

  .hero--dark .hero-legend {
    font-size: 10px;
    gap: 20px;
    bottom: 15px
  }

  .hero--dark .motion-toggle {
    width: 36px;
    height: 36px;
    right: 0;
    bottom: 6px
  }

  .hero--dark .hero-baseline {
    margin-top: 14px
  }

  .hero--dark .hero-description {
    font-size: 13px
  }

  .hero--dark .hero-copy {
    max-width: 100%
  }
}

/* Keep the original circular artwork in front of the right-side DNA background. */
.hero--dark #gene-canvas {
  opacity: .38
}

.hero--dark .hero-copy {
  position: relative;
  text-shadow: 0 2px 18px #0a1c3080
}

.hero--dark .hero-art {
  width: 100%;
  height: auto;
  aspect-ratio: 1;
  margin: 0;
  isolation: isolate
}

#orb-canvas {
  display: block;
  width: 100%;
  height: 100%
}

.hero--dark .gene-orb {
  border: 1px solid #6bc2f13d;
  box-shadow: inset 0 0 32px #6bc2f149, 0 25px 75px #06132380, 0 0 60px #5993d617
}

.hero--dark .orbital {
  border-color: #6bc2f14a
}

.hero--dark .orbital-two {
  border-color: #6bc2f12b
}

.hero--dark .orbit-label {
  background: #143352e8;
  border-color: #6bc2f14a;
  color: #e9f7fb;
  box-shadow: 0 12px 35px #05132255
}

.hero--dark .orbit-label svg {
  stroke: var(--sky)
}

.hero--dark .motion-toggle {
  right: 5%;
  bottom: 3%
}

@media(max-width:800px) {
  .hero--dark .hero-art {
    width: min(490px, 96%);
    height: auto;
    aspect-ratio: 1;
    margin: 24px auto 0
  }

  .hero--dark #gene-canvas {
    opacity: .3
  }

  .hero--dark .motion-toggle {
    right: 5%;
    bottom: 3%
  }
}

/* Editorial section designs. All rules below are scoped away from the hero. */
.section {
  position: relative;
  padding: 80px 0
}

.section>.container {
  position: relative;
  z-index: 1
}

.section h2 {
  font-weight: 650;
  line-height: 1.14;
  letter-spacing: -.05em
}

.section-intro {
  max-width: none;
  display: grid;
  grid-template-columns: 1.1fr 1fr;
  gap: 60px;
  align-items: end;
  margin-bottom: 56px
}

.section-intro h2 {
  margin: 0;
  max-width: 760px
}

.section-intro>p {
  font-size: 15px;
  line-height: 1.9;
  margin: 0;
  padding-bottom: 4px
}

.chapter-label {
  display: flex;
  align-items: center;
  gap: 13px;
  font-size: 10px;
  font-weight: 650;
  letter-spacing: .15em;
  color: #52718c;
  margin-bottom: 23px;
  line-height: 1.5
}

.chapter-label>span {
  width: 28px;
  height: 28px;
  display: grid;
  place-items: center;
  border: 1px solid #bdd4df;
  border-radius: 50%;
  letter-spacing: 0;
  font-size: 10px
}

.chapter-label>i {
  width: 28px;
  height: 1px;
  background: var(--aqua)
}

.dark .chapter-label {
  color: #a2d1df
}

.dark .chapter-label>span {
  border-color: #6ac7ce55
}

.section-title.compact h2 {
  font-size: clamp(34px, 3.5vw, 48px)
}

.section .notice {
  background: #ffffff70;
  border: 1px solid #d6e5ed;
  border-left: 3px solid var(--aqua);
  padding: 18px 22px;
  border-radius: 0 10px 10px 0;
  font-size: 11px
}

.dark .notice {
  background: #ffffff05;
  border-color: #9fcfe92b;
  border-left-color: var(--aqua);
  color: #bed4e3
}

.spotlight-card {
  position: relative;
  isolation: isolate;
  overflow: hidden
}

.spotlight-card::after {
  content: "";
  position: absolute;
  inset: 0;
  background: radial-gradient(500px circle at var(--pointer-x, 50%) var(--pointer-y, 0%), #6bc2f11c, transparent 65%);
  opacity: 0;
  pointer-events: none;
  z-index: -1;
  transition: opacity .35s
}

.spotlight-card:hover::after {
  opacity: 1
}

/* Four connected pillars. */
.highlights {
  background: linear-gradient(180deg, #f5f9fc, #fff);
  padding-top: 78px;
  padding-bottom: 95px;
  overflow: hidden
}

.highlights:before {
  content: "";
  position: absolute;
  top: 0;
  right: 0;
  width: 40%;
  height: 1px;
  background: linear-gradient(90deg, transparent, var(--aqua), transparent)
}

.highlights-grid {
  border: 0;
  border-radius: 0;
  overflow: visible;
  gap: 18px;
  align-items: stretch;
  padding-bottom: 24px
}

.highlight {
  padding: 30px 27px 34px;
  border: 1px solid #d5e4ed;
  border-radius: 20px;
  box-shadow: 0 15px 35px #14335206;
  transition: transform .4s, box-shadow .4s, border-color .4s;
  min-width: 0
}

.highlight+.highlight {
  border-left: 1px solid #d5e4ed
}

.highlight:nth-child(even) {
  top: 24px;
  background: #edf6f9
}

.highlight:first-child {
  background: linear-gradient(145deg, #164689, #143352);
  color: #d8e8f3;
  border-color: transparent
}

.highlight:first-child h3 {
  color: #fff
}

.highlight:first-child .icon-box {
  background: #ffffff10;
  color: var(--ice);
  border-color: #9ecce455
}

.highlight:first-child sup a {
  color: var(--ice)
}

.highlight:nth-child(3) {
  background: linear-gradient(140deg, #e4f4f3, #fff)
}

.highlight-top {
  display: flex;
  align-items: center;
  justify-content: space-between;
  margin-bottom: 35px
}

.highlight .icon-box {
  width: 56px;
  height: 56px;
  margin: 0;
  border-radius: 17px;
  float: none;
  transition: transform .4s
}

.highlight-number {
  font-size: 58px;
  line-height: 1;
  font-weight: 500;
  letter-spacing: -.08em;
  color: #88acbf45
}

.highlight:first-child .highlight-number {
  color: #a6e0e738
}

.highlight h3 {
  font-size: 19px;
  line-height: 1.4;
  min-height: 108px;
  margin: 0 0 18px
}

.highlight p {
  font-size: 14px;
  line-height: 1.9;
  clear: none
}

.card-rail {
  display: block;
  position: absolute;
  bottom: 0;
  left: 26px;
  right: 26px;
  height: 3px;
  background: linear-gradient(90deg, var(--aqua), #5993d633);
  border-radius: 3px
}

.highlight:hover {
  transform: translateY(-8px);
  box-shadow: 0 24px 45px #16468912;
  border-color: #87c4d8
}

.highlight:hover .icon-box {
  transform: rotate(-8deg)
}

/* Investor overview: a layered laboratory image and a clean reading column. */
.overview {
  background: radial-gradient(ellipse at 12% 60%, #d9edf2, transparent 55%), #f6f9fb;
  overflow: hidden
}

.overview-grid {
  grid-template-columns: .95fr 1.05fr;
  gap: 90px
}

.overview-visual {
  min-height: 600px;
  margin: 10px 28px 40px 0;
  isolation: isolate
}

.overview-visual>img {
  border-radius: 180px 180px 24px 24px;
  object-position: 37%;
  position: relative;
  box-shadow: 0 30px 60px #16468918
}

.overview-orbit {
  position: absolute;
  inset: -28px;
  border: 1px solid #6ac7ce66;
  border-radius: 220px 220px 40px 40px;
  z-index: -1;
  transform: rotate(-7deg)
}

.overview-orbit:before {
  content: "";
  position: absolute;
  right: 3%;
  top: 17%;
  width: 12px;
  height: 12px;
  background: var(--aqua);
  border: 3px solid #f6f9fb;
  border-radius: 50%;
  box-shadow: 0 0 0 6px #6ac7ce22
}

.overview-inset {
  position: absolute;
  right: -48px;
  bottom: -28px;
  width: 47%;
  aspect-ratio: 1.1;
  border: 7px solid #f6f9fb;
  border-radius: 23px;
  overflow: hidden;
  box-shadow: 0 15px 30px #14335212
}

.overview-inset img {
  width: 100%;
  height: 100%;
  object-fit: cover
}

.overview .visual-corner {
  left: 24px;
  bottom: 92px;
  width: 68px;
  height: 68px;
  background: #143352d9;
  color: #b6e7ed;
  border: 1px solid #ffffff40
}

.overview .visual-corner svg {
  width: 38px;
  color: #b6e7ed
}

.visual-tag {
  position: absolute;
  left: 20px;
  bottom: 24px;
  display: flex;
  align-items: center;
  gap: 8px;
  padding: 13px 16px;
  background: #ffffffed;
  backdrop-filter: blur(10px);
  border: 1px solid #fff;
  border-radius: 8px;
  color: var(--navy);
  font-size: 10px;
  letter-spacing: .05em;
  font-weight: 600;
  box-shadow: 0 10px 25px #14335212
}

.visual-tag i {
  width: 6px;
  height: 6px;
  border-radius: 50%;
  background: #3697a4
}

.overview-copy h2 {
  font-size: clamp(36px, 4vw, 54px);
  margin-bottom: 26px
}


.overview-copy>p:first-of-type {
  font-size: 18px;
  line-height: 1.7;
  color: var(--navy);
  letter-spacing: -.02em;
  border-left: 2px solid var(--aqua);
  padding-left: 20px;
  margin-bottom: 24px
}

/* The seven reasons: an asymmetric feature mosaic. */
.reasons {
  background: radial-gradient(ellipse at 90% 20%, #164689b3, transparent 55%), linear-gradient(145deg, #0c243c, #143352)
}

.reasons:before {
  content: "";
  position: absolute;
  inset: 0;
  background-image: radial-gradient(#c1e2ea16 1px, transparent 1px);
  background-size: 28px 28px;
  mask-image: linear-gradient(90deg, transparent, #000);
  pointer-events: none
}

.reasons .section-title {
  margin-bottom: 50px
}

.reason-orbits {
  right: 30px;
  top: -20px;
  width: 245px;
  height: 245px;
  animation: section-rotate 45s linear infinite
}

.reasons-grid {
  grid-template-columns: repeat(12, minmax(0, 1fr));
  gap: 20px
}

.reason {
  display: block;
  grid-column: span 6;
  padding: 34px;
  border-radius: 21px;
  border-color: #85b4cf30;
  background: linear-gradient(140deg, #ffffff08, #ffffff02);
  box-shadow: inset 0 1px 0 #ffffff05;
  transition: transform .4s, border-color .4s, background .4s
}

.reason-top {
  display: flex;
  justify-content: space-between;
  align-items: center;
  margin-bottom: 24px
}

.reason-index {
  width: auto;
  height: auto;
  border: 0;
  border-radius: 0;
  font-size: 42px;
  line-height: 1;
  letter-spacing: -.07em;
  font-weight:700;
  color: #6ac7ce9e
}

.reason-icon {
  width: 43px;
  height: 43px;
  display: grid;
  place-items: center;
  border: 1px solid #80c6da35;
  border-radius: 13px;
  color: #a2dbe5
}

.reason-icon svg {
  width: 26px;
  height: 26px
}

.reason h3 {
  font-size: 22px;
  margin-bottom: 16px
}

.reason p {
  font-size: 14px;
  line-height: 1.9
}

.reason-1 {
  grid-column: span 5;
  grid-row: span 2;
  padding: 38px;
  background: linear-gradient(145deg, #276980c4, #16468961);
  border-color: #8dcbd648;
  display: flex;
  flex-direction: column
}

.reason-1 .reason-top {
  width: 100%
}

.reason-1 .reason-index {
  background: transparent;
  color: #b3ebed
}

.reason-1 h3 {
  font-size: 30px;
  line-height: 1.2
}

.reason-1 .reason-copy {
  max-width: 100%
}

.reason-1>div {
  max-width: none
}

.reason-2,
.reason-3 {
  grid-column: span 7
}

.reason-2 .reason-top,
.reason-3 .reason-top {
  margin-bottom: 18px
}

.reason-2 h3,
.reason-3 h3 {
  font-size: 24px
}

.reason-4,
.reason-7 {
  background: linear-gradient(135deg, #6ac7ce0d, #ffffff02)
}

.reason:hover {
  transform: translateY(-5px);
  border-color: #83cedd73;
  background-color: #ffffff05
}

.molecule-art {
  position: relative;
  width: 230px;
  height: 210px;
  margin: 25px auto 0;
  flex-shrink: 0
}

.molecule-art i {
  position: absolute;
  inset: 18%;
  border: 1px solid #8ed4e079;
  border-radius: 50%;
  transform: rotate(-30deg) scaleX(.48);
  animation: section-orbit-a 18s linear infinite
}

.molecule-art i:nth-of-type(2) {
  transform: rotate(30deg) scaleX(.48);
  animation: section-orbit-b 23s linear infinite
}

.molecule-art i:nth-of-type(3) {
  transform: rotate(90deg) scaleX(.48);
  animation: section-orbit-c 28s linear infinite
}

.molecule-core {
  position: absolute;
  inset: 35%;
  border-radius: 50%;
  background: radial-gradient(circle at 30% 25%, #c1e2ea, #6ac7ce 40%, #164689);
  box-shadow: 0 0 50px #6ac7ce35, inset -8px -8px 15px #14335266;
  animation: section-breathe 7s ease-in-out infinite
}

.molecule-art b {
  position: absolute;
  width: 10px;
  height: 10px;
  border: 2px solid #6ac7ce;
  border-radius: 50%;
  background: #143352;
  top: 20%;
  left: 32%;
  box-shadow: 0 0 15px #6ac7ce45
}

.molecule-art b:nth-of-type(2) {
  top: 70%;
  left: 70%;
  width: 7px;
  height: 7px
}

.molecule-art b:nth-of-type(3) {
  top: 50%;
  left: 18%;
  width: 6px;
  height: 6px
}

.reason-1 .molecule-art {
  margin-top: auto;
  padding-top: 25px;
  height: 220px
}

/* Two disease areas, each with its original chart. */
.challenges {
  background: #fff;
  overflow: hidden
}

.challenges:after {
  content: "";
  position: absolute;
  right: -190px;
  top: 70px;
  width: 460px;
  height: 460px;
  border: 1px solid #b4d8e42b;
  border-radius: 50%;
  box-shadow: 0 0 0 45px #c1e2ea0b, 0 0 0 90px #c1e2ea09
}

.challenge-grid {
  gap: 30px
}

.challenge {
  border-radius: 25px;
  border-color: #cfdee8;
  box-shadow: 0 18px 45px #14335208;
  transition: transform .4s, box-shadow .4s
}



.challenge-grid {
  padding-bottom: 55px
}

.challenge-image {
  position: relative;
  height: 255px;
  overflow: hidden;
  background-size: cover
}

.challenge-image:after {
  content: "";
  position: absolute;
  inset: 0;
  background: linear-gradient(0deg, #1433529c, transparent 75%)
}

.image-label {
  position: absolute;
  z-index: 1;
  left: 28px;
  bottom: 25px;
  padding: 7px 12px;
  border-radius: 5px;
  border: 1px solid #ffffff55;
  background: #14335255;
  backdrop-filter: blur(8px);
  color: #fff;
  font-size: 10px;
  letter-spacing: .14em
}

.challenge-body {
  padding: 34px
}

.challenge h3 {
  font-size: 27px;
  line-height: 1.25;
  margin-bottom: 23px
}

.challenge p {
  line-height: 1.9
}

.challenge .document-figure {
  border-top: 1px solid var(--line);
  padding-top: 23px;
  margin-top: 28px;
  background: #fff
}

.challenge:hover {
  transform: translateY(-5px);
  box-shadow: 0 26px 50px #14335210
}

.zoom-symbol {
  width: 36px;
  height: 36px;
  background: var(--navy);
  color: var(--ice);
  border-color: #ffffff44;
  box-shadow: 0 4px 12px #14335220
}

/* The science: lab-style panels, original diagrams, and editorial quotations. */
.science {
  background: radial-gradient(ellipse at 0 50%, #c1e2ea5c, transparent 60%), #f0f6f9
}

.science-row {
  gap: 0;
  grid-template-columns: 1fr 1fr;
  background: #fff;
  border: 1px solid #d9e6ed;
  border-radius: 26px;
  overflow: hidden;
  margin-top: 28px;
  box-shadow: 0 12px 35px #14335204
}

.science-copy {
  padding: 40px
}

.science-label {
  display: flex;
  align-items: center;
  justify-content: space-between;
  margin-bottom: 27px;
  border-bottom: 1px solid var(--line);
  padding-bottom: 20px
}

.science-label>span {
  font-size: 10px;
  letter-spacing: .16em;
  font-weight: 650;
  color: var(--blue)
}

.science-copy .icon-box {
  margin: 0;
  border: 0;
  background: #edf7f8;
  width: 42px;
  height: 42px
}

.science-copy .icon-box svg {
  width: 27px
}

.science-copy h3 {
  font-size: 29px;
  margin-bottom: 20px
}

.science-copy p {
  line-height: 1.95
}

.science-stage {
  align-self: stretch;
  display: flex;
  align-items: center;
  padding: 28px;
  background-image: linear-gradient(#5993d60b 1px, transparent 1px), linear-gradient(90deg, #5993d60b 1px, transparent 1px), linear-gradient(145deg, #e9f3f8, #f6fbfc);
  background-size: 24px 24px, 24px 24px, auto;
  position: relative;
  min-width: 0
}

.science-stage:before {
  content: "";
  position: absolute;
  inset: 15%;
  border: 1px dashed #6ac7ce70;
  border-radius: 50%;
  animation: section-rotate 65s linear infinite
}

.science-row .document-figure {
  position: relative;
  z-index: 1;
  width: 100%;
  padding: 16px;
  border: 1px solid #cddfe9;
  border-radius: 18px;
  background: #fff;
  box-shadow: 0 16px 30px #16468912;
  transition: transform .5s
}

.science-row:hover .document-figure {
  transform: translateY(-5px)
}

.quote-panel {
  position: relative;
  border-radius: 22px;
  background: linear-gradient(135deg, #163c60, #164689);
  padding: 43px 48px;
  gap: 38px;
  border: 1px solid #5993d650;
  color: #e1edf4;
  overflow: hidden;
  box-shadow: 0 18px 45px #1433520d
}

.quote-panel:after {
  content: "";
  width: 220px;
  height: 220px;
  position: absolute;
  right: -60px;
  bottom: -90px;
  border: 1px solid #6ac7ce30;
  border-radius: 50%;
  box-shadow: 0 0 0 30px #6ac7ce08, 0 0 0 60px #6ac7ce05;
  pointer-events: none
}

.quote-person {
  width: 110px
}

.quote-person img {
  width: 100px;
  height: 100px;
  border: 4px solid #ffffff15;
  box-shadow: 0 0 0 1px #99d4e044
}



.quote-panel blockquote {
  position: relative;
  z-index: 1
}

.quote-panel blockquote p {
  color: #e4eff6;
  font-size: 16px;
  line-height: 1.9;
  font-weight: 400
}

.quote-panel cite {
  color: #a8dce6;
  font-size: 12px;
  letter-spacing: .02em
}

.quote-panel sup a {
  color: var(--ice)
}

/* Clinical programs: parallel treatment cards with paired therapy labels. */
.clinical {
  background: #fff
}

.clinical-grid {
  gap: 24px;
  align-items: stretch
}

.trial-card {
  padding: 0 34px 34px;
  border-radius: 23px;
  border: 1px solid #d1e1eb;
  background: #fff;
  box-shadow: 0 18px 45px #16468907;
  position: relative
}

.trial-top {
  margin: 0 -34px 28px;
  padding: 24px 34px;
  background: linear-gradient(110deg, #143352, #164689);
  color: #d6f1f5;
  border: 0;
  font-size: 14px;
  letter-spacing: .16em
}

.trial-top svg {
  width: 31px
}

.trial-card:nth-child(2) {
  background: linear-gradient(150deg, #f6fbfc, #eaf6f6)
}

.trial-card:nth-child(2) .trial-top {
  background: linear-gradient(110deg, #286674, #164689)
}

.therapy-pair {
  display: flex;
  gap: 11px;
  align-items: center;
  margin: 0 0 27px;
  font-size: 10px;
  color: var(--blue);
  letter-spacing: .06em;
  font-weight: 650
}

.therapy-pair>span {
  padding: 6px 12px;
  border: 1px solid #c1dae6;
  border-radius: 30px;
  background: #f0f7fa
}

.therapy-pair>i {
  font-size: 18px;
  font-style: normal;
  color: #559cae
}

.trial-card h3 {
  font-size: 28px;
  line-height: 1.25;
  margin-bottom: 23px
}

.trial-card p {
  line-height: 1.95
}

.trial-card .document-figure {
  padding: 12px;
  border: 1px solid #d5e4ed;
  border-radius: 13px;
  margin-top: 30px;
  background: #fff
}

.trial-molecule {
  width: 240px;
  height: 200px;
  margin: 20px auto 0
}

.trial-molecule .molecule-core {
  box-shadow: 0 0 45px #6ac7ce40
}

.trial-molecule i {
  border-color: #5993d688
}

.trial-molecule b {
  background: #f2f8fb
}

.clinical-conclusion {
  border: 1px solid #cddfe9;
  border-left: 4px solid var(--aqua);
  border-radius: 0 16px 16px 0;
  background: #f4f9fb;
  padding: 30px 34px;
  margin-top: 30px;
  align-items: center
}

/* Pipeline: a framed research board. */
.pipeline {
  background: radial-gradient(ellipse at 100% 100%, #c1e2ea5e, transparent 65%), #f1f6f9;
  overflow: hidden
}

.pipeline-frame {
  background: #123454;
  border: 1px solid #1e5279;
  padding: 15px;
  border-radius: 22px;
  box-shadow: 0 28px 55px #14335218;
  position: relative
}

.pipeline-toolbar {
  display: flex;
  justify-content: space-between;
  align-items: center;
  padding: 13px 15px 26px;
  color: #b7d9e6;
  font-size: 10px;
  letter-spacing: .12em
}

.pipeline-toolbar span {
  display: flex;
  align-items: center;
  gap: 12px
}

.pipeline-toolbar i {
  height: 6px;
  width: 6px;
  background: var(--aqua);
  border-radius: 50%;
  box-shadow: 0 0 12px #6ac7ce80
}

.pipeline-toolbar b {
  font-weight: 400;
  color: #5993d6
}

.pipeline-frame .document-figure {
  max-width: none;
  padding: 18px;
  background: #fff;
  border-radius: 11px
}

.pipeline-frame .image-zoom {
  border-radius: 0
}

.pipeline-frame:after {
  content: "";
  position: absolute;
  left: 15%;
  right: 15%;
  bottom: -1px;
  height: 2px;
  background: linear-gradient(90deg, transparent, var(--aqua), transparent);
  animation: section-signal 6s ease-in-out infinite
}

/* Market opportunity: two oversized circular figures. */
.market {
  background: linear-gradient(110deg, #0d2943e6, #0d2943b8), url("../images/pexels-andrea-piacquadio-3823542.jpg") center / cover no-repeat;
  overflow: hidden
}

.market:before {
  content: "";
  position: absolute;
  right: -160px;
  top: 30px;
  width: 600px;
  height: 600px;
  border: 1px solid #6ac7ce17;
  border-radius: 50%;
  box-shadow: 0 0 0 60px #6ac7ce04, 0 0 0 120px #6ac7ce03
}

.market-grid {
  gap: 26px
}

.market-card {
  position: relative;
  border: 1px solid #84b4cc36;
  padding: 38px;
  border-radius: 24px;
  overflow: hidden;
  background: linear-gradient(140deg, #1b487c8f, #0000004f);
  isolation: isolate
}

.market-card:nth-child(2) {
  background: linear-gradient(140deg, #22a6af3d, #0000005c);
}

.market-number {
  position: relative;
  z-index: 1;
  font-size: clamp(80px, 8vw, 116px);
  line-height: 1.3;
  margin-bottom: 28px;
  font-weight: 450;
  color: #d0f1f4
}

.market-number span {
  color: var(--aqua)
}

.market-number svg {
  width: 40px;
  height: 40px;
  padding: 7px;
  border: 1px solid #6ac7ce40;
  border-radius: 50%
}

.market-card h3 {
  position: relative;
  z-index: 1;
  font-size: 27px;
  line-height: 1.3;
  margin-top: 12px
}

.market-card p {
  position: relative;
  z-index: 1;
  line-height: 1.95
}

.market-orbit {
  position: absolute;
  width: 290px;
  height: 290px;
  border: 1px dashed #6ac7ce33;
  border-radius: 50%;
  top: -120px;
  right: -60px;
  box-shadow: 0 0 0 25px #6ac7ce04, 0 0 0 50px #6ac7ce03;
  animation: section-rotate 70s linear infinite
}

.market-orbit:before {
  content: "";
  position: absolute;
  left: 20%;
  bottom: 7%;
  width: 8px;
  height: 8px;
  background: var(--aqua);
  border-radius: 50%;
  box-shadow: 0 0 15px #6ac7ce66
}

/* Research updates: a chronological editorial layout. */
.developments {
  background: #fff
}

.development-layout {
  grid-template-columns: .8fr 1.2fr;
  gap: 60px;
  align-items: start
}

.development-photo {
  min-height: 0;
  height: 660px;
  border-radius: 110px 22px 22px 22px;
  position: sticky;
  top: 35px;
  border: 1px solid #d7e5ed;
  box-shadow: 0 25px 50px #1433520b
}

.development-photo>img {
  object-position: 39%;
  transition: transform 1s
}

.development-photo:hover>img {
  transform: scale(1.035)
}

.development-photo .photo-grid {
  display: block;
  background: linear-gradient(0deg, #102e4beb, transparent 80%)
}

.photo-grid:after {
  width: 210px;
  height: 210px;
  bottom: 120px;
  left: calc(50% - 105px);
  border-color: #6ac7ce40;
  animation: section-breathe 8s ease-in-out infinite
}

.collaboration-tags {
  position: absolute;
  bottom: 28px;
  left: 27px;
  right: 27px;
  display: flex;
  gap: 10px;
  flex-wrap: wrap
}

.collaboration-tags span {
  border: 1px solid #b2dce747;
  padding: 8px 12px;
  border-radius: 7px;
  backdrop-filter: blur(8px);
  background: #16468945;
  color: #deedf4;
  font-size: 11px
}

.timeline:before {
  left: 23px;
  background: linear-gradient(#6ac7ce, #5993d6, #dbe9f0)
}

.development {
  gap: 24px;
  padding-bottom: 32px
}

.development:last-child {
  padding-bottom: 0
}

.timeline-node {
  width: 47px;
  height: 47px;
  background: #fff;
  border: 1px solid #c4dce8;
  box-shadow: 0 0 0 7px #fff;
  color: var(--blue);
  font-size: 12px
}

.development>div:last-child {
  border: 1px solid #dce8ef;
  border-radius: 16px;
  padding: 24px;
  background: linear-gradient(120deg, #f3f8fb, #fff);
  flex: 1;
  min-width: 0
}

.development-date {
  display: inline-block;
  font-size: 9px;
  letter-spacing: .1em;
  text-transform: uppercase;
  color: #377b95;
  background: #e6f2f5;
  border-radius: 4px;
  padding: 4px 9px;
  margin-bottom: 15px
}

.development h3 {
  font-size: 21px;
  line-height: 1.35;
  margin-bottom: 17px
}

.development p {
  font-size: 15px;
  line-height: 1.9
}

.compact-quote {
  margin-top: 50px
}

.compact-quote .quote-person>span {
  display: block
}

/* Upcoming milestones: a connected roadmap beside a persistent introduction. */
.milestones {
  background: radial-gradient(ellipse at 0 50%, #c1e2ea66, transparent 55%), #f3f8fa
}

.milestones>.container {
  display: grid;
  grid-template-columns: .8fr 1.2fr;
  gap: 78px;
  align-items: start
}

.milestones .section-intro {
  display: block;
  position: sticky;
  top: 35px;
  margin: 0
}

.milestones .section-intro h2 {
  font-size: clamp(35px, 3.1vw, 45px);
  margin-bottom: 27px
}

.milestones .section-intro>p {
  font-size: 15px;
  line-height: 1.95
}

.milestone-molecule {
  width: 260px;
  height: 235px;
  margin-top: 30px
}

.milestone-molecule i {
  border-color: #5993d670
}

.milestone-molecule b {
  background: #f3f8fa
}

.milestone-list {
  position: relative;
  border: 0;
  display: grid;
  gap: 20px
}

.milestone-list:before {
  content: "";
  position: absolute;
  top: 35px;
  bottom: 35px;
  left: 29px;
  width: 1px;
  background: linear-gradient(#6ac7ce, #5993d6, #c1e2ea)
}

.milestone {
  position: relative;
  border: 1px solid #d4e4ed;
  border-radius: 18px;
  gap: 20px;
  padding: 28px 25px;
  background: #fff;
  box-shadow: 0 8px 22px #14335204;
  transition: border-color .3s, transform .3s
}

.milestone-number {
  width: 48px;
  min-width: 48px;
  height: 48px;
  border: 1px solid #badbe6;
  background: #edf7f9;
  border-radius: 14px;
  display: grid;
  place-items: center;
  font-size: 21px;
  color: #397b98;
  letter-spacing: -.04em
}

.milestone h3 {
  font-size: 21px;
  line-height: 1.35;
  margin-bottom: 15px
}

.milestone p {
  font-size: 15px;
  line-height: 1.9
}

.milestone-plus {
  display: none
}

.milestone:first-child {
  border-color: #78bacd;
  background: linear-gradient(130deg, #edf8f9, #fff)
}

.milestone:first-child .milestone-number {
  background: var(--blue);
  color: #fff;
  border-color: var(--blue)
}

.milestone:hover {
  transform: translateX(4px);
  border-color: #78bacd
}

/* Company and leadership. */
.company {
  background: #fff
}

.company-grid {
  grid-template-columns: 1fr 1fr;
  gap: 70px;
  align-items: start
}

.company-heading .eyebrow {
  font-size: 11px
}

.company-heading h2 {
  font-size: 48px;
  line-height: 1.14
}

.company-heading>img {
  height: 240px;
  border-radius: 22px 80px 22px 22px;
  margin-top: 35px;
  box-shadow: 0 16px 35px #1433520b
}
.company-heading>img.second{
  margin-top: 10px;
  border-radius: 22px 80px 22px 282px;
}
.company-copy {
  padding: 28px 30px;
  border: 1px solid #dce8ef;
  border-radius: 22px;
  background: linear-gradient(130deg, #f2f8fb, #fff)
}

.company-copy p {
  line-height: 1.95
}

.company-copy>p:first-child {
  color: var(--navy);
  font-size: 16px
}

.team-heading {
  margin: 75px 0 30px
}

.team-heading h2 {
  font-size: 38px
}

.team-grid {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  gap: 18px
}

.team-card {
  border: 1px solid #dce8ef;
  border-radius: 16px;
  overflow: hidden;
  background: #fff;
  box-shadow: 0 8px 22px #14335205;
  transition: transform .4s, box-shadow .4s
}

.team-photo {
  aspect-ratio: 1/1.12;
  overflow: hidden;
  background: #e9f2f6;
  position: relative
}

.team-photo:after {
  content: "";
  position: absolute;
  inset: 0;
  background: linear-gradient(0deg, #16468920, transparent 50%);
  pointer-events: none
}

.team-photo img {
  height: 100%;
  width: 100%;
  object-fit: cover;
  object-position: 50% 15%;
  transition: transform .7s
}

.team-bio {
  padding: 21px 17px;
  border-top: 3px solid #6ac7ce88
}

.team-bio h3 {
  font-size: 17px;
  line-height: 1.4;
  letter-spacing: -.025em;
  margin-bottom: 9px
}

.team-bio p {
  font-size: 13px;
  line-height: 1.65;
  color: #60758a
}

.team-card:hover {
  transform: translateY(-7px);
  box-shadow: 0 20px 30px #16468910
}

.team-card:hover img {
  transform: scale(1.045)
}





/* News: a photographic article grid with each original URL preserved. */
.news {
  background: #f0f6f9
}

.news-list {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 24px
}

.news-link {
  display: block;
  padding: 0;
  border: 1px solid #d4e3ec;
  border-radius: 18px;
  overflow: hidden;
  background: #fff;
  box-shadow: 0 8px 25px #14335205;
  transition: transform .4s, box-shadow .4s, border-color .4s
}

.news-image {
  position: relative;
  height: 185px;
  overflow: hidden;
  background: #dbeaf0
}

.news-image:after {
  content: "";
  position: absolute;
  inset: 0;
  background: linear-gradient(0deg, #14335255, transparent 70%)
}

.news-image img {
  width: 100%;
  height: 100%;
  object-fit: cover;
  transition: transform .7s
}

.news-number {
  position: absolute;
  z-index: 1;
  bottom: 14px;
  left: 18px;
  display: grid;
  place-items: center;
  width: 30px;
  height: 30px;
  border: 1px solid #ffffff60;
  border-radius: 50%;
  color: #fff;
  background: #14335255;
  font-size: 10px
}

.news-content {
  position: relative;
  padding: 25px 25px 58px;
  min-height: 200px
}

.news-source {
  display: block;
  font-size: 9px;
  letter-spacing: .16em;
  font-weight: 650;
  color: #51819b;
  margin-bottom: 15px
}

.news-content>span[data-source-p] {
  display: block;
  font-size: 14px;
  line-height: 1.8;
  overflow-wrap: anywhere;
  color: var(--navy)
}

.news-arrow {
  position: absolute;
  right: 20px;
  bottom: 17px;
  width: 31px;
  height: 31px;
  border: 1px solid #cbdfe9;
  border-radius: 50%;
  font-size: 19px;
  display: grid;
  place-items: center;
  line-height: 1;
  background: #f0f7fa;
  transition: background .3s, color .3s
}

.news-link:hover {
  transform: translateY(-6px);
  background: #fff;
  box-shadow: 0 18px 38px #16468912;
  border-color: #89bfd2
}

.news-link:hover .news-image img {
  transform: scale(1.055)
}

.news-link:hover .news-arrow {
  background: var(--blue);
  color: #fff
}

/* Summary and final investor resources. */
.summary {
  background: #fff
}

.summary-layout {
  grid-template-columns: .7fr 1.3fr;
  gap: 65px;
  align-items: start
}

.summary-title h2 {
  font-size: 54px
}

.summary-symbol {
  width: 180px;
  height: 180px;
  margin-top: 38px;
  background: radial-gradient(circle at 30% 30%, #e1f5f6, #e5eff9);
  border: 1px solid #b8dce7;
  box-shadow: 0 0 0 18px #c1e2ea13, 0 0 0 36px #c1e2ea0a;
  position: relative
}

.summary-symbol:after {
  content: "";
  position: absolute;
  inset: -20px;
  border: 1px dashed #5993d633;
  border-radius: 50%;
  animation: section-rotate 50s linear infinite
}

.summary-symbol svg {
  width: 84px
}

.summary-points {
  display: grid;
  gap: 16px
}

.summary-point {
  display: flex;
  gap: 20px;
  padding: 24px;
  border: 1px solid #dbe7ef;
  border-radius: 15px;
  background: linear-gradient(120deg, #f3f8fb, #fff)
}

.summary-point>span {
  font-size: 12px;
  letter-spacing: .04em;
  color: #40849e;
  flex-shrink: 0;
  padding-top: 3px
}

.summary-point p {
  font-size: 14px;
  line-height: 1.9
}

.closing {
  padding: 100px 0;
  background: radial-gradient(ellipse at 50% 120%, #2c8da26e, transparent 60%), radial-gradient(ellipse at 90% 0, #164689, transparent 60%), #102e4e;
  overflow: hidden
}

.closing h2 {
  font-size: clamp(26px, 2.8vw, 38px);
  max-width: 1080px;
  line-height: 1.3;
  position: relative;
  z-index: 1
}

.closing-orbits {
  inset: -100px 28%;
  border-color: #8bd4df25;
  box-shadow: 0 0 0 55px #81c4d209, 0 0 0 110px #81c4d207;
  animation: section-orbit-b 60s linear infinite
}

.closing .primary-button {
  border-radius: 50px;
  padding: 16px 30px;
  background: linear-gradient(100deg, var(--aqua), var(--ice));
  box-shadow: 0 8px 32px #6ac7ce20;
  gap: 45px;
  font-size: 15px
}

.closing .primary-button:hover {
  box-shadow: 0 14px 40px #6ac7ce3b
}

.closing-actions {
  margin-top: 42px;
  gap: 22px
}

.resource-links {
  gap: 12px;
  margin-top: 30px
}

.resource-links a {
  padding: 12px 18px;
  border: 1px solid #b5d7e22e;
  border-radius: 8px;
  background: #ffffff05;
  text-decoration: none;
  transition: background .3s
}

.resource-links a:hover {
  background: #ffffff12;
  text-decoration: underline
}

.sources {
  padding: 50px 0;
  background: #f8fbfc
}

.sources h2 {
  font-size: 23px
}

.sources ol {
  gap: 12px 16px
}

.sources li {
  padding: 13px 15px;
  border: 1px solid #e0eaf0;
  background: #fff;
  border-radius: 8px;
  align-items: start;
  line-height: 1.7
}

.source-number {
  display: grid;
  place-items: center;
  background: #edf5f8;
  border-radius: 5px;
  min-width: 26px;
  min-height: 26px;
  color: #4c819d
}

.sources a {
  font-size: 10px;
  align-self: center;
  text-decoration: none
}

.sources a:hover {
  text-decoration: underline
}

.site-footer {
  background: #f8fbfc;
  color: #637e92;
  border-color: #e0eaf0
}

/* Motion is limited to visible sections, and respects the existing pause control. */
@keyframes section-rotate {
  to {
    transform: rotate(360deg)
  }
}

@keyframes section-orbit-a {
  from {
    transform: rotate(-30deg) scaleX(.48)
  }

  to {
    transform: rotate(330deg) scaleX(.48)
  }
}

@keyframes section-orbit-b {
  from {
    transform: rotate(30deg) scaleX(.48)
  }

  to {
    transform: rotate(390deg) scaleX(.48)
  }
}

@keyframes section-orbit-c {
  from {
    transform: rotate(90deg) scaleX(.48)
  }

  to {
    transform: rotate(450deg) scaleX(.48)
  }
}

@keyframes section-breathe {

  0%,
  100% {
    transform: scale(1)
  }

  50% {
    transform: scale(1.07)
  }
}

@keyframes section-signal {

  0%,
  100% {
    opacity: .4;
    transform: scaleX(.6)
  }

  50% {
    opacity: 1;
    transform: scaleX(1)
  }
}

.section:not(.section-active) .molecule-art *,
.section:not(.section-active) .reason-orbits,
.section:not(.section-active) .market-orbit,
.section:not(.section-active) .closing-orbits,
.section:not(.section-active) .science-stage:before,
.section:not(.section-active) .pipeline-frame:after,
.section:not(.section-active) .photo-grid:after,
.section:not(.section-active) .summary-symbol:after {
  animation-play-state: paused
}

@media(max-width:1100px) {
  .section {
    padding: 85px 0
  }

  .section-intro {
    gap: 35px
  }

  .section h2 {
    font-size: 39px
  }

  .section-intro>p {
    font-size: 14px
  }

  .highlights-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
    gap: 20px
  }

  .highlight:nth-child(even) {
    top: 18px
  }

  .highlight h3 {
    min-height: 0
  }

  .highlight-top {
    margin-bottom: 25px
  }

  .overview-grid {
    gap: 48px
  }

  .overview-visual {
    min-height: 570px;
    margin-right: 15px
  }

  .overview-inset {
    right: -30px
  }

  .overview-copy>p:first-of-type {
    font-size: 16px
  }

  .reason {
    padding: 27px
  }

  .reason-1 {
    grid-column: span 5;
    padding: 28px
  }

  .reason-2,
  .reason-3 {
    grid-column: span 7
  }

  .reason-1 h3 {
    font-size: 26px
  }

  .reason-2 h3,
  .reason-3 h3 {
    font-size: 22px
  }

  .reason h3 {
    font-size: 22px
  }

  .science-copy {
    padding: 28px
  }

  .science-copy h3 {
    font-size: 26px
  }

  .science-stage {
    padding: 20px
  }

  .quote-panel {
    padding: 35px;
    gap: 28px
  }

  .market-card {
    padding: 30px
  }

  .market-number {
    font-size: 90px
  }

  .development-layout {
    gap: 35px
  }

  .development-photo {
    height: 610px
  }

  .development>div:last-child {
    padding: 21px
  }

  .milestones>.container {
    gap: 35px;
    grid-template-columns: .8fr 1.2fr
  }

  .milestones .section-intro h2 {
    font-size: 35px
  }

  .milestone {
    padding: 23px 20px;
    gap: 15px
  }

  .milestone-number {
    width: 38px;
    min-width: 38px;
    height: 38px;
    font-size: 18px
  }

  .company-grid {
    gap: 35px
  }

  .company-heading h2 {
    font-size: 39px
  }

  .company-copy {
    padding: 24px
  }

  .team-grid {
    grid-template-columns: repeat(3, minmax(0, 1fr));
    gap: 20px
  }

  .team-card:nth-child(4) {
    grid-column: 1
  }

  .team-bio h3 {
    font-size: 18px
  }

  .news-list {
    gap: 18px
  }

  .news-content {
    padding: 22px 20px 58px
  }

  .news-image {
    height: 165px
  }

  .summary-layout {
    gap: 40px
  }

  .summary-title h2 {
    font-size: 46px
  }
}

@media(max-width:800px) {
  .section {
    padding: 70px 0
  }

  .section-intro {
    grid-template-columns: 1fr;
    gap: 24px;
    margin-bottom: 38px
  }

  .section h2 {
    font-size: 37px
  }

  .chapter-label {
    margin-bottom: 22px;
    font-size: 9px
  }

  .overview-grid {
    grid-template-columns: 1fr;
    gap: 55px
  }

  .overview-visual {
    height: 450px;
    min-height: 0;
    width: 85%;
    max-width: 490px;
    justify-self: center;
    margin: 20px 30px 20px 0
  }

  .overview-visual>img {
    border-radius: 160px 160px 22px 22px;
    object-position: 40% 40%
  }

  .overview-copy h2 {
    font-size: 42px
  }

  .reasons-grid {
    grid-template-columns: 1fr 1fr
  }

  .reason {
    grid-column: auto
  }

  .reason-1 {
    grid-column: 1/-1;
    grid-row: auto;
    display: block;
    padding: 32px 260px 32px 32px;
    min-height: 350px
  }

  .reason-1 .molecule-art {
    position: absolute;
    right: 10px;
    bottom: calc(50% - 110px);
    width: 230px;
    margin: 0
  }

  .reason-1 .reason-copy {
    position: relative;
    z-index: 1
  }

  .reason-1 .reason-top {
    width: 100%
  }

  .reason-2,
  .reason-3 {
    grid-column: auto
  }

  .reason-1 h3 {
    font-size: 27px
  }

  .reason h3 {
    font-size: 21px
  }

  .reason p {
    font-size: 13px
  }

  .reasons .section-title h2 {
    font-size: 45px
  }

  .challenge-grid {
    grid-template-columns: 1fr;
    gap: 28px;
    padding-bottom: 0
  }

  .challenge:nth-child(2) {
    margin: 0
  }

  .challenge-image {
    height: 260px
  }

  .challenge-body {
    padding: 30px
  }

  .challenge .document-figure {
    max-width: none
  }

  .challenge p {
    font-size: 14px
  }

  .science-row {
    grid-template-columns: 1fr
  }

  .science-copy {
    padding: 30px
  }

  .science-stage {
    padding: 30px;
    min-height: 300px
  }

  .science-row.reverse .science-copy {
    order: 0
  }

  .science-row .document-figure {
    max-width: 570px;
    margin: auto
  }

  .quote-panel {
    padding: 30px;
    gap: 24px
  }

  .quote-person {
    width: 80px
  }

  .quote-person img {
    width: 75px;
    height: 75px
  }

  .quote-panel blockquote p {
    font-size: 15px
  }

  .clinical-grid {
    grid-template-columns: 1fr
  }

  .trial-card {
    padding: 0 30px 30px
  }

  .trial-top {
    margin-inline: -30px;
    padding-inline: 30px
  }

  .trial-card .document-figure {
    max-width: 580px;
    margin-inline: auto
  }

  .trial-molecule {
    height: 180px
  }

  .clinical-conclusion {
    grid-template-columns: 1fr;
    gap: 16px;
    padding: 26px
  }

  .market-grid {
    gap: 20px
  }

  .market-card {
    padding: 25px
  }

  .market-number {
    font-size: 73px
  }

  .market-number svg {
    width: 31px;
    height: 31px
  }

  .market-card h3 {
    font-size: 24px
  }

  .market-card p {
    font-size: 13px
  }

  .development-layout {
    grid-template-columns: 1fr;
    gap: 35px
  }

  .development-photo {
    position: relative;
    top: auto;
    height: 350px;
    min-height: 0;
    border-top-left-radius: 75px
  }

  .development-photo>img {
    object-position: center 37%
  }

  .photo-grid:after {
    display: none
  }

  .collaboration-tags {
    bottom: 24px
  }

  .development h3 {
    font-size: 22px
  }

  .development p {
    font-size: 14px
  }

  .milestones>.container {
    grid-template-columns: 1fr;
    gap: 35px
  }

  .milestones .section-intro {
    position: relative;
    top: auto
  }

  .milestones .section-intro h2 {
    font-size: 37px;
    max-width: 600px
  }

  .milestone-molecule {
    display: none
  }

  .milestone {
    padding: 27px;
    gap: 22px
  }

  .milestone-number {
    width: 46px;
    min-width: 46px;
    height: 46px;
    font-size: 20px
  }

  .milestone h3 {
    font-size: 23px
  }

  .milestone p {
    font-size: 14px
  }

  .company-grid {
    grid-template-columns: 1fr;
    gap: 30px
  }

  .company-heading h2 {
    max-width: 550px;
    font-size: 42px
  }

  .company-heading>img {
    height: 300px
  }

  .company-copy {
    padding: 28px
  }

  .company-copy p {
    font-size: 14px
  }

  .team-grid {
    grid-template-columns: repeat(3, minmax(0, 1fr));
    gap: 15px
  }

  .team-bio {
    padding: 18px 13px
  }

  .team-bio h3 {
    font-size: 16px
  }

  .team-bio p {
    font-size: 10px
  }

  .news-list {
    grid-template-columns: repeat(2, minmax(0, 1fr));
    gap: 20px
  }

  .news-content {
    min-height: 210px
  }

  .news-content>span[data-source-p] {
    font-size: 12px
  }

  .news-image {
    height: 185px
  }

  .summary-layout {
    grid-template-columns: 1fr;
    gap: 30px
  }

  .summary-symbol {
    display: none
  }

  .summary-title h2 {
    font-size: 42px
  }

  .summary-point {
    padding: 25px
  }

  .closing h2 {
    font-size: 28px
  }

  .closing {
    padding: 75px 0
  }

  .sources ol {
    grid-template-columns: 1fr
  }
}

@media(max-width:480px) {
  .section {
    padding: 55px 0
  }

  .section h2 {
    font-size: 32px
  }

  .section-intro {
    gap: 22px;
    margin-bottom: 30px
  }

  .section-intro>p {
    font-size: 13px;
    line-height: 1.9
  }

  .chapter-label {
    gap: 9px;
    font-size: 8px;
    letter-spacing: .12em;
    margin-bottom: 18px
  }

  .chapter-label>span {
    height: 24px;
    width: 24px;
    font-size: 9px
  }

  .chapter-label>i {
    width: 20px
  }

  .section .notice {
    padding: 15px 17px;
    font-size: 10px;
    margin-top: 28px
  }

  .highlights-grid {
    grid-template-columns: 1fr;
    padding: 0;
    gap: 16px
  }

  .highlight {
    padding: 25px;
    border-radius: 17px
  }

  .highlight:nth-child(even) {
    top: 0
  }

  .highlight+.highlight {
    border: 1px solid #d5e4ed
  }

  .highlight-top {
    margin-bottom: 23px
  }

  .highlight .icon-box {
    width: 48px;
    height: 48px;
    float: none;
    margin: 0
  }

  .highlight-number {
    font-size: 54px
  }

  .highlight h3 {
    font-size: 21px;
    min-height: 0;
    margin-bottom: 15px
  }

  .highlight p {
    font-size: 13px
  }

  .overview-visual {
    height: 350px;
    width: 86%;
    margin-top: 10px;
    margin-right: 25px;
    margin-bottom: 20px
  }

  .overview-orbit {
    inset: -15px;
    transform: rotate(-5deg)
  }

  .overview-inset {
    right: -28px;
    bottom: -25px;
    width: 50%;
    border-width: 5px;
    border-radius: 17px
  }

  .overview .visual-corner {
    width: 50px;
    height: 50px;
    left: 16px;
    bottom: 81px;
    border-radius: 13px
  }

  .overview .visual-corner svg {
    width: 30px
  }

  .visual-tag {
    left: 10px;
    bottom: 17px;
    padding: 9px 11px;
    font-size: 8px
  }

  .overview-grid {
    gap: 40px
  }

  .overview-copy h2 {
    font-size: 36px
  }

  .overview-copy p {
    font-size: 13px
  }

  .overview-copy>p:first-of-type {
    font-size: 16px;
    line-height: 1.75;
    padding-left: 16px
  }

  .reasons .section-title h2 {
    font-size: 36px
  }

  .reasons .section-title {
    margin-bottom: 30px
  }

  .reasons-grid {
    grid-template-columns: 1fr;
    gap: 16px
  }

  .reason,
  .reason-1,
  .reason-2,
  .reason-3 {
    grid-column: auto;
    padding: 26px;
    min-height: 0
  }

  .reason-top {
    margin-bottom: 24px
  }

  .reason-index {
    font-size: 36px;
    margin: 0
  }

  .reason-icon {
    width: 39px;
    height: 39px
  }

  .reason h3,
  .reason-1 h3 {
    font-size: 24px
  }

  .reason p {
    font-size: 13px
  }

  .reason-1 .molecule-art {
    position: relative;
    right: auto;
    bottom: auto;
    margin: 15px auto 0;
    height: 180px;
    width: 210px
  }

  .reason-orbits {
    display: none
  }

  .challenge-image {
    height: 200px
  }

  .challenge {
    border-radius: 20px
  }

  .challenge-body {
    padding: 20px 15px;
  }

  .challenge h3 {
    font-size: 25px
  }

  .challenge p {
    font-size: 13px
  }

  .image-label {
    left: 22px;
    bottom: 20px;
    font-size: 9px
  }

  .science-row {
    border-radius: 20px;
    margin-top: 20px
  }

  .science-copy {
    padding: 25px
  }

  .science-copy h3 {
    font-size: 25px
  }

  .science-copy p {
    font-size: 13px
  }

  .science-label {
    margin-bottom: 23px
  }

  .science-label>span {
    font-size: 9px
  }

  .science-stage {
    padding: 18px;
    min-height: 0
  }

  .science-row .document-figure {
    padding: 9px;
    border-radius: 12px
  }

  .quote-panel {
    padding: 27px;
    display: block;
    border-radius: 18px;
    margin-top: 35px
  }

  .quote-person {
    width: auto;
    display: flex;
    gap: 20px;
    margin-bottom: 20px;
    align-items: center
  }

  .quote-person img {
    width: 68px;
    height: 68px
  }

  .quote-person>span {
    font-size: 85px;
    height: 60px;
    margin: 0
  }

  .quote-panel blockquote p {
    font-size: 14px;
    line-height: 1.95
  }

  .quote-panel cite {
    font-size: 11px
  }

  .trial-card {
    padding: 0 24px 25px;
    border-radius: 19px
  }

  .trial-top {
    margin: 0 -24px 25px;
    padding: 22px 24px;
    font-size: 12px
  }

  .trial-card h3 {
    font-size: 25px
  }

  .trial-card p {
    font-size: 13px
  }

  .therapy-pair {
    gap: 8px;
    font-size: 9px;
    margin-bottom: 22px
  }

  .therapy-pair>span {
    padding: 6px 10px
  }

  .clinical-conclusion {
    padding: 23px
  }

  .clinical-conclusion h3 {
    font-size: 23px
  }

  .clinical-conclusion p {
    font-size: 13px
  }

  .pipeline-frame {
    padding: 8px;
    border-radius: 14px
  }

  .pipeline-toolbar {
    padding: 12px 5px 19px;
    font-size: 8px;
    letter-spacing: .06em;
    gap: 10px
  }

  .pipeline-toolbar span {
    gap: 6px
  }

  .pipeline-frame .document-figure {
    padding: 5px;
    border-radius: 7px
  }

  .market-grid {
    grid-template-columns: 1fr;
    gap: 20px
  }

  .market-card {
    padding: 27px;
    border-radius: 20px
  }

  .market-number {
    font-size: 96px;
    margin-bottom: 25px
  }

  .market-card h3 {
    font-size: 26px
  }

  .market-card p {
    font-size: 13px
  }

  .market-orbit {
    width: 250px;
    height: 250px;
    top: -90px
  }

  .development-photo {
    height: 300px;
    border-top-left-radius: 65px
  }

  .collaboration-tags {
    left: 20px;
    right: 20px;
    bottom: 22px;
    gap: 7px
  }

  .collaboration-tags span {
    padding: 7px 10px;
    font-size: 10px
  }

  .development {
    gap: 6px;
    padding-bottom: 22px
  }

  .timeline-node {
    width: 32px;
    height: 32px;
    min-width: 32px;
    font-size: 10px;
    box-shadow: 0 0 0 4px #fff
  }

  .timeline:before {
    left: 16px
  }

  .development>div:last-child {
    padding: 20px;
    border-radius: 13px
  }

  .development-date {
    font-size: 8px;
    letter-spacing: .06em;
    padding: 4px 7px
  }

  .development h3 {
    font-size: 20px
  }

  .development p {
    font-size: 12px;
    line-height: 1.9
  }

  .milestones .section-intro h2 {
    font-size: 32px
  }

  .milestones .section-intro>p {
    font-size: 13px
  }

  .milestone {
    padding: 23px 20px;
    gap: 15px;
    border-radius: 15px
  }

  .milestone-number {
    width: 32px;
    min-width: 32px;
    height: 32px;
    font-size: 15px;
    border-radius: 9px
  }

  .milestone h3 {
    font-size: 20px
  }

  .milestone p {
    font-size: 12px;
    line-height: 1.95
  }

  .milestone:hover {
    transform: none
  }

  .company-heading h2 {
    font-size: 35px
  }

  .company-heading>img {
    height: 240px;
    border-top-right-radius: 60px
  }

  .company-copy {
    padding: 24px
  }

  .company-copy p {
    font-size: 13px
  }

  .company-copy>p:first-child {
    font-size: 15px
  }

  .team-heading {
    margin-top: 45px
  }

  .team-heading h2 {
    font-size: 32px
  }

  .team-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
    gap: 14px
  }

  .team-card:nth-child(4) {
    grid-column: auto
  }

  .team-card:last-child {
    grid-column: 1/-1;
    width: calc(50% - 7px);
    justify-self: center
  }

  .team-bio {
    padding: 17px 13px
  }

  .team-bio h3 {
    font-size: 15px
  }

  .team-bio p {
    font-size: 10px
  }

  .news-list {
    grid-template-columns: 1fr;
    gap: 22px
  }

  .news-image {
    height: 200px
  }

  .news-content {
    min-height: 0;
    padding: 23px 24px 60px
  }

  .news-content>span[data-source-p] {
    font-size: 13px
  }

  .news-source {
    font-size: 9px
  }

  .news-link {
    border-radius: 17px
  }

  .summary-title h2 {
    font-size: 37px
  }

  .summary-point {
    padding: 22px;
    gap: 14px
  }

  .summary-point p {
    font-size: 13px
  }

  .summary-point>span {
    font-size: 11px
  }

  .summary-points {
    gap: 14px
  }

  .closing h2 {
    font-size: 24px;
    line-height: 1.4
  }

  .closing .primary-button {
    padding: 14px 22px;
    font-size: 14px;
    gap: 25px
  }

  .closing-actions {
    margin-top: 30px
  }

  .resource-links a {
    font-size: 12px;
    padding: 12px;
    overflow-wrap: anywhere
  }

  .sources {
    padding: 35px 0
  }

  .sources li {
    padding: 12px;
    gap: 10px
  }

  .sources a {
    font-size: 10px
  }

  .sources h2 {
    font-size: 23px
  }
}

@media(prefers-reduced-motion:reduce) {

  .section *,
  .section *:before,
  .section *:after {
    animation: none !important;
    transition: none !important
  }

  .highlight:hover,
  .reason:hover,
  .challenge:hover,
  .milestone:hover,
  .team-card:hover,
  .news-link:hover {
    transform: none
  }
}

.skip-link:not(:focus) {
  clip-path: inset(50%);
  width: 1px;
  height: 1px;
  overflow: hidden
}

@media(max-width:480px) {
  .market-number {
    font-size: clamp(70px, 21vw, 96px)
  }

  .market-number svg {
    flex-shrink: 0
  }

  .milestone {
    display: block;
    padding: 25px
  }

  .milestone-number {
    margin-bottom: 18px;
    width: 38px;
    height: 38px;
    font-size: 17px
  }

  .milestone h3 {
    font-size: 22px
  }

  .milestone p {
    font-size: 14px;
    line-height: 1.9
  }

  .development p {
    font-size: 13px
  }

  .team-bio p {
    font-size: 11px
  }
}

/* Charts, Source, disclaimer and footer adapted from html-amfn. */
.charts-section {
  background: #f2f1ed;
  padding: 22px 0 30px
}

.charts-section>.container,
.cc-source>.container,
.disclaimer-section>.container,
.site-footer>.container {
  width: 100%;
  max-width: 1200px;
  padding: 0 20px;
  margin-inline: auto
}

.charts-section>.container {
  max-width: 1320px
}

.charts {
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  align-items: flex-start
}

.charts .chart {
  min-width: 0
}

.charts .chartone {
  width: 100%;
  margin-bottom: 30px
}

.charts .charttwo {
  width: 48%
}

.charts .tradingview-widget-container {
  position: relative;
  width: 100%;
  min-width: 0
}

.chartone .tradingview-widget-container {
  min-height: 200px
}

.chartone.chart-ready .tradingview-widget-container {
  min-height: 0
}

.charttwo .tradingview-widget-container,
.charttwo .tradingview-widget-container__widget,
#tradingview-gnpx-price {
  height: 500px;
  width: 100%
}

.charts .charttwo iframe {
  height: 500px !important;
  width: 100% !important;
  max-width: 100%;
  border: 0
}

.charts .chartone iframe {
  width: 100% !important;
  max-width: 100%;
  border: 0
}

.chart-status {
  position: absolute;
  inset: 0;
  display: flex;
  align-items: center;
  justify-content: center;
  text-align: center;
  background: #f7fafc;
  color: #47637c;
  font-size: 13px;
  padding: 25px;
  border: 1px solid #dce7ee;
  z-index: 1;
  pointer-events: none;
  line-height: 1.8
}

.chart-status[hidden] {
  display: none
}

.chart-provider {
  font-size: 11px;
  padding: 9px 0;
  color: #56738a;
  line-height: 1.6
}

.chart-provider a {
  color: var(--blue);
  text-decoration: none
}

.chart-provider a:hover {
  text-decoration: underline
}

.chart-ready .chart-provider {
  display: none
}

.chart-noscript {
  font-size: 13px;
  color: var(--navy);
  margin-top: 12px
}

.cc-source.section {
  padding: 40px 0 0;
  background: #fff
}

.cc-source h2 {
  font-size: 18px;
  font-weight: 700;
  color: var(--navy);
  letter-spacing: normal;
  line-height: 1.4;
  margin: 0 0 20px
}

.cc-source p {
  color: var(--navy);
  padding: 6px 0;
  margin: 0;
  font-size: 14px;
  line-height: 1.7;
  overflow-wrap: anywhere;
  word-break: break-word;
  scroll-margin-top: 30px
}

.cc-source a {
  color: inherit;
  text-decoration: none
}

.cc-source a:hover {
  text-decoration: underline
}

.disclaimer-section {
  padding: 60px 24px 80px;
  background: #fff;
  scroll-margin-top: 25px
}

.disclaimer-section .sources {
  padding: 0;
  background: transparent
}

.disclaimer-section .disclaimer-title {
  font-size: 18px;
  font-weight: 700;
  color: var(--navy);
  margin: 0 0 20px;
  letter-spacing: normal;
  line-height: 1.5;
  font-family: var(--font)
}

.disclaimer-section .sources p {
  font-size: 12px;
  color: #143352;
  line-height: 1.8;
  margin: 0 0 14px;
  overflow-wrap: anywhere
}

.site-footer {
  background: #000;
  border: 0;
  text-align: center;
  padding: 15px;
  color: #fff
}

.site-footer p {
  font-size: 14px;
  color: #fff;
  line-height: 1.7;
  margin: 0
}

@media(max-width:1024px) {
  .charts .charttwo {
    width: 100%;
    margin-bottom: 15px
  }
}

@media(max-width:768px) {
  .charts-section {
    padding: 22px 0 25px
  }

  .charttwo .tradingview-widget-container,
  .charttwo .tradingview-widget-container__widget,
  #tradingview-gnpx-price {
    height: 350px
  }

  .charts .charttwo iframe {
    height: 350px !important
  }

  .cc-source.section {
    padding: 50px 0
  }

  .cc-source h2 {
    font-size: 16px
  }

  .cc-source p {
    font-size: 13px
  }

  .disclaimer-section {
    padding: 40px 16px 60px
  }
}

@media(max-width:480px) {
  .charts-section {
    padding: 20px 0
  }

  .disclaimer-section {
    padding: 30px 12px 40px
  }

  .chart-status {
    padding: 20px;
    font-size: 12px
  }

  .site-footer p {
    font-size: 12px
  }
}

/* News coverage: source-led cards. */
.section.news {
  background: linear-gradient(160deg, #122944, #091625);
  padding: 80px 0;
  color: #eef3fa
}



.news .news-list {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 24px
}

.news-card {
  display: flex;
  flex-direction: column;
  align-items: flex-start;
  min-width: 0;
  padding: 28px;
  border: 1px solid #19394c;
  border-radius: 17px;
  background: #0c1626;
  transition: transform .3s, border-color .3s, box-shadow .3s
}

.news-card:hover {
  transform: translateY(-5px);
  border-color: #6ac7ce88;
  box-shadow: 0 16px 36px #0003
}

.news-publisher {
  display: flex;
  align-items: center;
  gap: 12px;
  margin-bottom: 14px;
  min-height: 30px
}

.news-publisher img {
  width: 88px;
  height: 30px;
  object-fit: contain
}

.news-publisher span {
  font-size: 10px;
  color: #a6b8cd;
  padding-left: 12px;
  border-left: 1px solid #2c425b;
  line-height: 1.4
}

.news-card time {
  color: #91a4bc;
  font-size: 12px;
  line-height: 1.5;
  margin-bottom: 13px
}

.news-card h3 {
  font-size: 15px;
  line-height: 1.55;
  font-weight: 750;
  letter-spacing: -.025em;
  margin: 0 0 28px;
  color: #eef3fa
}

.news-card h3 a {
  color: inherit;
  text-decoration: none;
  transition: color .2s
}

.news-card h3 a:hover {
  color: #6bc2f1
}

.news-card .news-read {
  margin-top: auto;
  color: #6bc2f1;
  font-size: 14px;
  line-height: 1.5;
  font-weight: 650;
  text-decoration: none;
  display: inline-flex;
  gap: 5px;
  align-items: center;
  min-height: 28px
}

.news-read span {
  transition: transform .2s
}

.news-read:hover span {
  transform: translateX(4px)
}

.news-card a:focus-visible {
  outline: 2px solid #6ac7ce;
  outline-offset: 5px;
  border-radius: 2px
}

@media(max-width:1024px) {
  .news .news-list {
    grid-template-columns: repeat(2, minmax(0, 1fr))
  }
}

@media(max-width:600px) {
  .section.news {
    padding: 56px 0
  }

  .news .news-list {
    grid-template-columns: 1fr;
    gap: 20px
  }

  .news-card {
    padding: 26px
  }

  .news-card h3 {
    font-size: 15px
  }
}

@media(prefers-reduced-motion:reduce) {
  .news-card:hover {
    transform: none
  }
}

/* Mobile reading comfort and touch targets. */
@media (max-width: 1024px) {
  .team-bio p { font-size: 14px; line-height: 1.65; }
  .disclaimer-section .sources p { font-size: 14px; line-height: 1.8; }
  .section p.notice { font-size: 13px; line-height: 1.75; }
}
@media (max-width: 800px) {
  .hero--dark .hero-description,
  .section p[data-source-p],
  .summary-copy p { font-size: 16px; line-height: 1.8; }
  .section p.notice { font-size: 13px; line-height: 1.75; }
  .section.cc-source p { font-size: 14px; line-height: 1.8; overflow-wrap: anywhere; }
  .section .chapter-label { font-size: 10px; letter-spacing: .1em; }
  .news-card h3 { font-size: 17px; line-height: 1.55; }
  .news-card time { font-size: 14px; }
  .news-publisher span { font-size: 12px; }
  .news-card .news-read { min-height: 44px; font-size: 15px; }
  .motion-toggle { min-width: 44px; min-height: 44px; }
  .presentation-url, .resource-links a { font-size: 14px; line-height: 1.7; }
  .resource-links a { min-height: 44px; display: inline-flex; align-items: center; justify-content: center; }
  .site-footer { font-size: 13px; line-height: 1.7; }
  .team-bio h3 { font-size: 18px; }
}
@media (max-width: 480px) {
  .team-grid { grid-template-columns: 1fr; gap: 16px; }
  .team-card, .team-card:last-child { display: grid; grid-template-columns: 100px minmax(0, 1fr); width: 100%; grid-column: auto; justify-self: stretch; }
  .team-photo { aspect-ratio: auto; min-height: 148px; }
  .team-bio { padding: 18px 15px; border-top: 0; border-left: 3px solid #6ac7ce88; align-self: stretch; display: flex; flex-direction: column; justify-content: center; }
  .team-bio h3 { font-size: 16px; margin-bottom: 8px; }
  .team-bio p { font-size: 14px; }
  .news-card { padding: 24px; }
  .section-title.compact h2 { white-space: normal; }
}

/* Unmet need: two editorial disease profiles with original data panels. */
.section.challenges { background: radial-gradient(ellipse at 0 0, #c1e2ea55, transparent 48%), #f5f9fc; }
.challenges>.container { position: relative; z-index: 1; }
.challenges .section-intro { max-width: none; grid-template-columns: 1.25fr 1fr; gap: 60px; align-items: center; }
.challenges .section-intro>p { padding-left: 26px; border-left: 2px solid #6ac7ce; }
.challenges .challenge-grid { grid-template-columns: 1fr; gap: 40px; padding-bottom: 0; }
.challenges .challenge { display: grid; grid-template-columns: minmax(0, .8fr) minmax(0, 1.4fr); border-radius: 26px; border: 1px solid #d1e2ec; background: #fff; box-shadow: 0 16px 45px #14335209; }
.challenges .challenge:hover { transform: none; box-shadow: 0 20px 50px #14335215; }
.challenges .challenge-image { height: auto; min-height: 470px; background-position: center; }
.challenges .challenge-image:after { background: linear-gradient(180deg,#0c294b55,#0c294bd9 65%,#0c294bf5); }
.challenges .challenge:nth-child(2) { grid-template-columns: minmax(0, 1.4fr) minmax(0, .8fr); }
.challenges .challenge:nth-child(2) .challenge-image { order: 2; }
.challenges .challenge-image .image-label { top: 28px; left: 28px; bottom: auto; font-size: 11px; padding: 9px 14px; border-radius: 30px; }
.challenge-visual { position: relative; z-index: 1; height: 100%; min-height: inherit; display: flex; flex-direction: column; justify-content: flex-end; padding: 40px 32px; color: #fff; overflow: hidden; }
.challenge-stat { position: relative; margin-bottom: 38px; }
.challenge-stat strong { display: block; color: #c1e2ea; font-size: clamp(38px,4.6vw,65px); line-height: 1.08; letter-spacing: -.055em; font-weight: 650; }
.challenge-stat>span { display: block; max-width: 220px; margin-top: 14px; font-size: 16px; line-height: 1.6; color: #e0edf6; }
.challenge-program { display: flex; gap: 10px; align-items: center; border-top: 1px solid #ffffff33; padding-top: 22px; font-size: 10px; letter-spacing: .09em; color: #bfe6ec; }
.challenge-program>span { width: 6px; height: 6px; border-radius: 50%; background: #6ac7ce; box-shadow: 0 0 0 5px #6ac7ce22; flex-shrink: 0; }
.challenge-rings { position: absolute; width: 330px; height: 330px; top: 18%; left: -100px; opacity: .6; animation: challenge-breathe 7s ease-in-out infinite; pointer-events: none; }
.challenge-rings i { position: absolute; inset: 0; border: 1px solid #6ac7ce55; border-radius: 50%; }
.challenge-rings i:nth-child(2) { inset: 28px; border-style: dashed; }
.challenge-rings i:nth-child(3) { inset: 65px; box-shadow: 0 0 70px #6ac7ce22; }
.challenges .challenge-body { padding: 40px; min-width: 0; }
.challenges .challenge h3 { font-size: clamp(24px,2.3vw,32px); line-height: 1.25; margin-bottom: 24px; }
.challenges .challenge p { font-size: 16px; line-height: 1.8; }
.challenges .challenge .document-figure { margin-top: 30px; padding: 16px; background: #f2f7fa; border: 1px solid #dce8ef; border-radius: 14px; }
.challenges .challenge .image-zoom { border-radius: 6px; overflow: hidden; }
@keyframes challenge-breathe { 50% { transform: scale(1.07) translateY(-10px); opacity: .9; } }
.section:not(.section-active) .challenge-rings { animation-play-state: paused; }
@media(max-width:1024px) {
 .challenges .section-intro { gap: 30px; }
 .challenges .challenge-body { padding: 28px; }
 .challenge-visual { padding: 32px 24px; }
 .challenge-stat strong { font-size: 42px; }
}
@media(max-width:800px) {
 .challenges .section-intro { grid-template-columns: 1fr; gap: 24px; }
 .challenges .section-intro>p { padding-left: 20px; }
 .challenges .challenge,.challenges .challenge:nth-child(2) { grid-template-columns: 1fr; }
 .challenges .challenge:nth-child(2) .challenge-image { order: 0; }
 .challenges .challenge-image { min-height: 300px; background-position: center 40%; }
 .challenge-visual { min-height: 300px; padding: 90px 28px 26px; }
 .challenge-stat { margin-bottom: 20px; }
 .challenge-stat strong { font-size: 46px; }
 .challenge-stat>span { max-width: none; font-size: 15px; margin-top: 8px; }
 .challenge-program { padding-top: 15px; }
 .challenge-rings { left: auto; right: -90px; top: 10px; }
}
@media(max-width:480px) {
 .challenges .challenge { border-radius: 20px; }
 .challenges .challenge-body { padding: 24px 20px; }
 .challenges .challenge h3 { font-size: 25px; }
 .challenges .challenge .document-figure { padding: 7px; margin-top: 24px; }
 .challenges .challenge-image .image-label { left: 24px; top: 24px; }
 .challenge-visual { padding-left: 24px; padding-right: 24px; }
}
@media(prefers-reduced-motion:reduce) { .challenge-rings { animation: none; } }

/* Transparent header shares the hero's continuous dark background. */
.site-header {
  position: absolute;
  top: 0;
  left: 0;
  width: 100%;
  z-index: 10;
  background: transparent;
  border-bottom: 0;
}
.hero.hero--dark { padding-top: 120px; }
.site-header .ticker {
  border: 1px solid #6bc2f14d;
  background: #16468999;
  box-shadow: 0 6px 22px #00000018;
}
@media (max-width: 800px) {
  .hero.hero--dark { padding-top: 128px; }
}
@media (max-width: 480px) {
  .hero.hero--dark { padding-top: 110px; }
}

/* Vector UI icons avoid platform-specific emoji and font substitution. */
.ui-icon { display: inline-block; width: 1em; height: 1em; flex: 0 0 auto; vertical-align: -.125em; }
.primary-button>span:last-child, .news-read>span, .motion-toggle>span { display: inline-flex; align-items: center; justify-content: center; }
.zoom-symbol .ui-icon { width: 19px; height: 19px; }
.primary-button .ui-icon { width: 23px; height: 23px; }
.news-read .ui-icon { width: 18px; height: 18px; }
.motion-toggle .ui-icon { width: 19px; height: 19px; }
.dialog-close .ui-icon { width: 22px; height: 22px; }